Statistics on Biotechnology Use Results by fields of operation Business Sector Biotechnology indicators by company size. Unidades: specified in variables Fewer than 250 employees 250 or more employees Total 2021 No. of companies carrying out R&D in Biotechnology 1.155 145 1.299 %Companies according to biotechnology used: Genetic code 29,7 39,5 30,8 %Companies according to biotechnology used: Functional units 37,4 46,5 38,4 %Companies according to biotechnology used: Cellular and tissue culturing and engineering 20,1 33,3 21,5 %Companies according to biotechnology used: Bioprocesses 49,2 63,2 50,8 %Companies according to biotechnology used: Sub-cellular organisms 7,5 15,9 8,5 %Companies according to biotechnology used: Bio-computing 23,7 26,4 24 %Companies according to biotechnology used: Nanobiotechnology 12,2 11,1 12,1 %Companies according to biotechnology used: Other 17,2 14,6 16,9 Companies in which biotechnology activities are: Main and/or exclusive 544 15 559 Companies in which biotechnology activities are: A secondary line of business 191 39 230 Companies in which biotechnology activities are: A tool necessary for production 420 90 510 %Company by field(s) of ultimate application of biotechnology use: Human Health 45,9 42,3 45,5 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture 15,9 12,5 15,5 %Company by field(s) of ultimate application of biotechnology use: Food products 31,9 35,5 32,3 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production 24,1 20,8 23,8 %Company by field(s) of ultimate application of biotechnology use: Environment 16 12,5 15,6 %Company by field(s) of ultimate application of biotechnology use: Industry 13,9 12,5 13,7 Personnel in R&D in biotechnology (no. of persons) 9.560 6.190 15.750 Personnel in R&D in biotechnology (no. of persons): Research personnel 5.506 2.874 8.379 Personnel in R&D in biotechnology (no. of persons): Technical and auxiliary personnel 4.055 3.316 7.371 Personnel in R&D in biotechnology (no. of persons). Women 4.963 3.748 8.711 Personnel in R&D in biotechnology (no. of persons). Women: Research personnel 2.838 1.673 4.510 Personnel in R&D in biotechnology (no. of persons). Women: Technical and auxiliary personnel 2.125 2.075 4.200 Personnel in R&D in biotechnology (FTE) 6.711 4.817,6 11.528,6 Personnel in R&D in biotechnology (FTE): Research personnel 4.162,2 2.180,5 6.342,7 Personnel in R&D in biotechnology (FTE): Technical and auxiliary personnel 2.548,8 2.637,1 5.185,9 Personnel in R&D in biotechnology (FTE). Women 3.575,2 2.964,6 6.539,7 Personnel in R&D in biotechnology (FTE). Women: Research personnel 2.167,4 1.288,4 3.455,7 Personnel in R&D in biotechnology (FTE). Women: Technical and auxiliary personnel 1.407,8 1.676,2 3.084 Internal expenditure on R&D (thousands of euros) 593.445 445.137 1.038.582 1) By nature of the expense: Current expenses 531.987 408.103 940.091 1.1) Remuneration to research personnel 194.798 126.772 321.570 1.2) Remuneration to technical and auxiliary personnel 91.565 103.271 194.836 1.3) Other current expenses 245.624 178.061 423.685 2) By nature of the expense: Capital expenses 61.458 37.033 98.492 2.1) Land and buildings 7.788 2.411 10.199 2.2) Equipment and instruments 40.235 32.349 72.584 2.3) Acquisition of specific R&D software 3.600 2.121 5.721 2.4) Otros productos de propiedad intelectual específicos para I+D 9.835 152 9.987 1.1) By origin of the funds: Own funds 403.266 308.222 711.488 1.2) By origin of the funds: From companies 75.949 45.789 121.738 1.3) By origin of the funds: Public Administration funds 76.924 30.552 107.477 1.4) By origin of the funds: From Universities 192 0 192 1.5) By origin of the funds: From non profit private institutions 1.543 9.213 10.756 1.6) By origin of the funds: Foreign funds 35.570 51.360 86.931 Purchase of R&D services in biotechnology (thousands of euros) 75.599 69.958 145.557 Purchase of R&D services in biotechnology (thousands of euros): In Spain 53.934 41.981 95.915 Purchase of R&D services in biotechnology (thousands of euros): Abroad 21.665 27.977 49.642 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital 42,3 23,7 40,2 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information 13,1 13,9 13,2 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources 19,4 16 19 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain 11 15,3 11,5 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets 16,5 10,4 15,9 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels 17,8 10,4 17 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception 16,1 19,5 16,4 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements 41,2 34,8 40,5 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost 56,1 46,5 55 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting 22,3 18,7 21,9 % Companies with income of an international origin related to biotechnological activities 24,2 18,1 23,5 % Turnover representing income of an international origin related to biotechnological activities 10,6 0,8 1,9 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU 56 69,8 61,6 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries 44 30,2 38,4 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services 93,8 78,7 87,6 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain 4,9 19,6 10,9 % Income of an international origin related with activities according to the classification: Operating source abroad 0,6 1,8 1,1 % Income of an international origin related with activities according to the classification: Other 0,6 0 0,4 Notas: '.'=numeric piece of data equal to zero not resulting from rounding FTE: Full Time Equivalent Fuente: National Statistics Institute