Statistics on Biotechnology Use Results by fields of operation Business Sector Biotechnology indicators by company size. Unidades: specified in variables Fewer than 250 employees 250 or more employees Total 2021 No. of companies carrying out R&D in Biotechnology 1.226 122 1.348 %Companies according to biotechnology used: Genetic code 30,5 36 31 %Companies according to biotechnology used: Functional units 37,6 46,7 38,4 %Companies according to biotechnology used: Cellular and tissue culturing and engineering 20,5 33,6 21,7 %Companies according to biotechnology used: Bioprocesses 48,6 68,1 50,3 %Companies according to biotechnology used: Sub-cellular organisms 7,2 18 8,2 %Companies according to biotechnology used: Bio-computing 24 25,4 24,1 %Companies according to biotechnology used: Nanobiotechnology 11,8 11,5 11,8 %Companies according to biotechnology used: Other 17 10,7 16,4 Companies in which biotechnology activities are: Main and/or exclusive 639 22 661 Companies in which biotechnology activities are: A secondary line of business 166 22 188 Companies in which biotechnology activities are: A tool necessary for production 421 78 500 %Company by field(s) of ultimate application of biotechnology use: Human Health 45,8 45,9 45,8 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture 15,6 11,5 15,3 %Company by field(s) of ultimate application of biotechnology use: Food products 31,5 32 31,5 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production 24,1 19,6 23,7 %Company by field(s) of ultimate application of biotechnology use: Environment 16 11,5 15,5 %Company by field(s) of ultimate application of biotechnology use: Industry 13,4 13,1 13,4 Personnel in R&D in biotechnology (no. of persons) 10.473 5.271 15.744 Personnel in R&D in biotechnology (no. of persons): Research personnel 5.914 2.465 8.380 Personnel in R&D in biotechnology (no. of persons): Technical and auxiliary personnel 4.558 2.806 7.364 Personnel in R&D in biotechnology (no. of persons). Women 5.482 3.242 8.725 Personnel in R&D in biotechnology (no. of persons). Women: Research personnel 3.094 1.426 4.521 Personnel in R&D in biotechnology (no. of persons). Women: Technical and auxiliary personnel 2.388 1.816 4.204 Personnel in R&D in biotechnology (FTE) 7.354,4 4.168,8 11.523,2 Personnel in R&D in biotechnology (FTE): Research personnel 4.402,9 1.938,6 6.341,6 Personnel in R&D in biotechnology (FTE): Technical and auxiliary personnel 2.951,5 2.230,1 5.181,6 Personnel in R&D in biotechnology (FTE). Women 3.909,3 2.643,4 6.552,7 Personnel in R&D in biotechnology (FTE). Women: Research personnel 2.305,8 1.158,6 3.464,4 Personnel in R&D in biotechnology (FTE). Women: Technical and auxiliary personnel 1.603,5 1.484,8 3.088,3 Internal expenditure on R&D (thousands of euros) 648.976 388.911 1.037.887 1) By nature of the expense: Current expenses 577.758 361.713 939.471 1.1) Remuneration to research personnel 213.250 108.275 321.525 1.2) Remuneration to technical and auxiliary personnel 104.359 90.297 194.656 1.3) Other current expenses 260.148 163.141 423.290 2) By nature of the expense: Capital expenses 71.218 27.197 98.416 2.1) Land and buildings 8.904 1.246 10.150 2.2) Equipment and instruments 48.703 23.835 72.538 2.3) Acquisition of specific R&D software 3.749 1.963 5.713 2.4) Otros productos de propiedad intelectual específicos para I+D 9.862 153 10.015 1.1) By origin of the funds: Own funds 428.118 282.919 711.037 1.2) By origin of the funds: From companies 87.264 34.331 121.595 1.3) By origin of the funds: Public Administration funds 81.113 26.309 107.422 1.4) By origin of the funds: From Universities 192 0 192 1.5) By origin of the funds: From non profit private institutions 1.543 9.213 10.756 1.6) By origin of the funds: Foreign funds 50.745 36.139 86.884 Purchase of R&D services in biotechnology (thousands of euros) 77.001 68.440 145.440 Purchase of R&D services in biotechnology (thousands of euros): In Spain 54.755 41.115 95.870 Purchase of R&D services in biotechnology (thousands of euros): Abroad 22.246 27.324 49.570 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital 41,6 21,3 39,8 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information 12,5 12,3 12,5 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources 18,8 14,8 18,5 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain 10,9 14,8 11,2 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets 15,9 12,3 15,6 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels 17 11,5 16,5 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception 16,3 13,9 16,1 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements 40,8 32,8 40 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost 54,9 43,4 53,9 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting 21,7 18,8 21,5 % Companies with income of an international origin related to biotechnological activities 22,8 16,4 22,2 % Turnover representing income of an international origin related to biotechnological activities 9,1 0,8 1,9 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU 57,9 78 65,5 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries 42,1 22 34,5 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services 93,7 74,2 86,3 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain 5,2 23,6 12,2 % Income of an international origin related with activities according to the classification: Operating source abroad 0,5 2,1 1,1 % Income of an international origin related with activities according to the classification: Other 0,6 0 0,4 Notas: '.'=numeric piece of data equal to zero not resulting from rounding FTE: Full Time Equivalent Fuente: National Statistics Institute