Main variables	No. of employees	Total
No. of companies carrying out R&D in Biotechnology	Fewer than 250 employees	1.006
No. of companies carrying out R&D in Biotechnology	250 or more employees	73
No. of companies carrying out R&D in Biotechnology	Total	1.079
%Companies according to biotechnology used: Genetic code	Fewer than 250 employees	34
%Companies according to biotechnology used: Genetic code	250 or more employees	55
%Companies according to biotechnology used: Genetic code	Total	35
%Companies according to biotechnology used: Functional units	Fewer than 250 employees	44
%Companies according to biotechnology used: Functional units	250 or more employees	53
%Companies according to biotechnology used: Functional units	Total	44
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Fewer than 250 employees	25
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	250 or more employees	47
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Total	26
%Companies according to biotechnology used: Bioprocesses	Fewer than 250 employees	48
%Companies according to biotechnology used: Bioprocesses	250 or more employees	64
%Companies according to biotechnology used: Bioprocesses	Total	49
%Companies according to biotechnology used: Sub-cellular organisms	Fewer than 250 employees	8
%Companies according to biotechnology used: Sub-cellular organisms	250 or more employees	15
%Companies according to biotechnology used: Sub-cellular organisms	Total	8
%Companies according to biotechnology used: Bio-computing	Fewer than 250 employees	23
%Companies according to biotechnology used: Bio-computing	250 or more employees	23
%Companies according to biotechnology used: Bio-computing	Total	23
%Companies according to biotechnology used: Nanobiotechnology	Fewer than 250 employees	15
%Companies according to biotechnology used: Nanobiotechnology	250 or more employees	12
%Companies according to biotechnology used: Nanobiotechnology	Total	15
%Companies according to biotechnology used: Other	Fewer than 250 employees	12
%Companies according to biotechnology used: Other	250 or more employees	11
%Companies according to biotechnology used: Other	Total	12
Companies in which biotechnology activities are: Main and/or exclusive	Fewer than 250 employees	503
Companies in which biotechnology activities are: Main and/or exclusive	250 or more employees	16
Companies in which biotechnology activities are: Main and/or exclusive	Total	519
Companies in which biotechnology activities are: A secondary line of business	Fewer than 250 employees	158
Companies in which biotechnology activities are: A secondary line of business	250 or more employees	21
Companies in which biotechnology activities are: A secondary line of business	Total	179
Companies in which biotechnology activities are: A tool necessary for production	Fewer than 250 employees	345
Companies in which biotechnology activities are: A tool necessary for production	250 or more employees	36
Companies in which biotechnology activities are: A tool necessary for production	Total	381
%Company by field(s) of ultimate application of biotechnology use: Human Health	Fewer than 250 employees	47
%Company by field(s) of ultimate application of biotechnology use: Human Health	250 or more employees	51
%Company by field(s) of ultimate application of biotechnology use: Human Health	Total	48
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Fewer than 250 employees	22
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	250 or more employees	4
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Total	21
%Company by field(s) of ultimate application of biotechnology use: Food products	Fewer than 250 employees	33
%Company by field(s) of ultimate application of biotechnology use: Food products	250 or more employees	34
%Company by field(s) of ultimate application of biotechnology use: Food products	Total	33
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Fewer than 250 employees	22
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	250 or more employees	21
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Total	22
%Company by field(s) of ultimate application of biotechnology use: Environment	Fewer than 250 employees	17
%Company by field(s) of ultimate application of biotechnology use: Environment	250 or more employees	21
%Company by field(s) of ultimate application of biotechnology use: Environment	Total	17
%Company by field(s) of ultimate application of biotechnology use: Industry	Fewer than 250 employees	15
%Company by field(s) of ultimate application of biotechnology use: Industry	250 or more employees	8
%Company by field(s) of ultimate application of biotechnology use: Industry	Total	15
Personnel in R&D in biotechnology (no. of persons)	Fewer than 250 employees	7.556
Personnel in R&D in biotechnology (no. of persons)	250 or more employees	2.239
Personnel in R&D in biotechnology (no. of persons)	Total	9.795
Personnel in R&D in biotechnology (no. of persons): Researchers	Fewer than 250 employees	4.379
Personnel in R&D in biotechnology (no. of persons): Researchers	250 or more employees	1.194
Personnel in R&D in biotechnology (no. of persons): Researchers	Total	5.573
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Fewer than 250 employees	3.177
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	250 or more employees	1.045
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Total	4.222
Personnel in R&D in biotechnology (no. of persons): women	Fewer than 250 employees	4.032
Personnel in R&D in biotechnology (no. of persons): women	250 or more employees	1.267
Personnel in R&D in biotechnology (no. of persons): women	Total	5.298
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Fewer than 250 employees	2.279
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	250 or more employees	646
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Total	2.925
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Fewer than 250 employees	1.752
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	250 or more employees	621
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Total	2.373
Personnel in R&D in biotechnology (FTE)	Fewer than 250 employees	5.209,9
Personnel in R&D in biotechnology (FTE)	250 or more employees	1.618,7
Personnel in R&D in biotechnology (FTE)	Total	6.828,6
Personnel in R&D in biotechnology (FTE): Researchers	Fewer than 250 employees	3.191,6
Personnel in R&D in biotechnology (FTE): Researchers	250 or more employees	914,9
Personnel in R&D in biotechnology (FTE): Researchers	Total	4.106,5
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Fewer than 250 employees	2.018,3
Personnel in R&D in biotechnology (FTE): Technicians and assistants	250 or more employees	703,8
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Total	2.722,1
Personnel in R&D in biotechnology (FTE): women	Fewer than 250 employees	2.872,2
Personnel in R&D in biotechnology (FTE): women	250 or more employees	939,6
Personnel in R&D in biotechnology (FTE): women	Total	3.811,7
Personnel in R&D in biotechnology (FTE): (women) Researchers	Fewer than 250 employees	1.682,6
Personnel in R&D in biotechnology (FTE): (women) Researchers	250 or more employees	508,1
Personnel in R&D in biotechnology (FTE): (women) Researchers	Total	2.190,7
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Fewer than 250 employees	1.189,5
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	250 or more employees	431,5
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Total	1.621
Internal expenditure on R&D (thousands of euros)	Fewer than 250 employees	402.391
Internal expenditure on R&D (thousands of euros)	250 or more employees	131.434
Internal expenditure on R&D (thousands of euros)	Total	533.826
1) By nature of the expense: Current expenses	Fewer than 250 employees	365.997
1) By nature of the expense: Current expenses	250 or more employees	126.959
1) By nature of the expense: Current expenses	Total	492.955
1.1) Remuneration to researchers	Fewer than 250 employees	153.274
1.1) Remuneration to researchers	250 or more employees	50.166
1.1) Remuneration to researchers	Total	203.439
1.2) Remuneration to technicians and assistants	Fewer than 250 employees	67.291
1.2) Remuneration to technicians and assistants	250 or more employees	29.559
1.2) Remuneration to technicians and assistants	Total	96.850
1.3) Other current expenses	Fewer than 250 employees	145.432
1.3) Other current expenses	250 or more employees	47.234
1.3) Other current expenses	Total	192.666
2) By nature of the expense: Capital expenses	Fewer than 250 employees	36.395
2) By nature of the expense: Capital expenses	250 or more employees	4.476
2) By nature of the expense: Capital expenses	Total	40.870
2.1) Land and buildings	Fewer than 250 employees	6.634
2.1) Land and buildings	250 or more employees	888
2.1) Land and buildings	Total	7.521
2.2) Equipment and instruments	Fewer than 250 employees	28.690
2.2) Equipment and instruments	250 or more employees	3.388
2.2) Equipment and instruments	Total	32.078
2.3) Acquisition of specific R&D software	Fewer than 250 employees	1.071
2.3) Acquisition of specific R&D software	250 or more employees	200
2.3) Acquisition of specific R&D software	Total	1.270
1) By origin of the funds: National funds	Fewer than 250 employees	329.975
1) By origin of the funds: National funds	250 or more employees	102.895
1) By origin of the funds: National funds	Total	432.869
1.1) Own funds	Fewer than 250 employees	239.006
1.1) Own funds	250 or more employees	80.039
1.1) Own funds	Total	319.046
1.2) From companies	Fewer than 250 employees	30.715
1.2) From companies	250 or more employees	8.538
1.2) From companies	Total	39.253
1.3) Public Administration funds	Fewer than 250 employees	57.667
1.3) Public Administration funds	250 or more employees	12.396
1.3) Public Administration funds	Total	70.063
1.4) From Universities	Fewer than 250 employees	156
1.4) From Universities	250 or more employees	0
1.4) From Universities	Total	156
1.5) From non profit private institutions	Fewer than 250 employees	2.431
1.5) From non profit private institutions	250 or more employees	1.921
1.5) From non profit private institutions	Total	4.351
1) By origin of the funds: Foreign funds	Fewer than 250 employees	72.416
1) By origin of the funds: Foreign funds	250 or more employees	28.540
1) By origin of the funds: Foreign funds	Total	100.956
2.1) From EU programmes	Fewer than 250 employees	18.073
2.1) From EU programmes	250 or more employees	1.998
2.1) From EU programmes	Total	20.070
2.2) Other foreign funds	Fewer than 250 employees	54.344
2.2) Other foreign funds	250 or more employees	26.542
2.2) Other foreign funds	Total	80.886
Purchase of R&D services in biotechnology (thousands of euros)	Fewer than 250 employees	76.625
Purchase of R&D services in biotechnology (thousands of euros)	250 or more employees	62.000
Purchase of R&D services in biotechnology (thousands of euros)	Total	138.625
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Fewer than 250 employees	64.575
Purchase of R&D services in biotechnology (thousands of euros): In Spain	250 or more employees	36.539
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Total	101.114
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Fewer than 250 employees	12.050
Purchase of R&D services in biotechnology (thousands of euros): Abroad	250 or more employees	25.462
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Total	37.512
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Fewer than 250 employees	48
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	250 or more employees	25
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Total	46
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Fewer than 250 employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	250 or more employees	10
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Total	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Fewer than 250 employees	12
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	250 or more employees	12
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Total	12
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Fewer than 250 employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	250 or more employees	17
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Total	14
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Fewer than 250 employees	19
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	250 or more employees	18
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Total	19
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Fewer than 250 employees	20
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	250 or more employees	12
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Total	19
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Fewer than 250 employees	18
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	250 or more employees	21
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Total	18
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Fewer than 250 employees	37
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	250 or more employees	36
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Total	37
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Fewer than 250 employees	50
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	250 or more employees	44
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Total	49
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Fewer than 250 employees	20
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	250 or more employees	11
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Total	19
% Companies that have requested biotechnology patents in Biotechnology	Fewer than 250 employees	15
% Companies that have requested biotechnology patents in Biotechnology	250 or more employees	22
% Companies that have requested biotechnology patents in Biotechnology	Total	15
Number of patents requested	Fewer than 250 employees	397
Number of patents requested	250 or more employees	69
Number of patents requested	Total	466
% Companies with income of an international origin related to biotechnological activities	Fewer than 250 employees	25,3
% Companies with income of an international origin related to biotechnological activities	250 or more employees	20,5
% Companies with income of an international origin related to biotechnological activities	Total	24,9
% Turnover representing income of an international origin related to biotechnological activities	Fewer than 250 employees	4
% Turnover representing income of an international origin related to biotechnological activities	250 or more employees	0,7
% Turnover representing income of an international origin related to biotechnological activities	Total	0,9
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Fewer than 250 employees	49,5
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	250 or more employees	81
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Total	71,3
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Fewer than 250 employees	50,5
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	250 or more employees	19,1
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Total	28,7
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Fewer than 250 employees	76,2
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	250 or more employees	99,2
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Total	92,2
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Fewer than 250 employees	7,8
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	250 or more employees	.
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Total	2,4
% Income of an international origin related with activities according to the classification: Operating source abroad	Fewer than 250 employees	3,2
% Income of an international origin related with activities according to the classification: Operating source abroad	250 or more employees	0,4
% Income of an international origin related with activities according to the classification: Operating source abroad	Total	1,3
% Income of an international origin related with activities according to the classification: Other	Fewer than 250 employees	12,7
% Income of an international origin related with activities according to the classification: Other	250 or more employees	0,4
% Income of an international origin related with activities according to the classification: Other	Total	4,2