Main variables	No. of employees	Total
No. of companies carrying out R&D in Biotechnology	Fewer than 250 employees	1.061
No. of companies carrying out R&D in Biotechnology	250 or more employees	73
No. of companies carrying out R&D in Biotechnology	Total	1.133
%Companies according to biotechnology used: Genetic code	Fewer than 250 employees	30
%Companies according to biotechnology used: Genetic code	250 or more employees	50
%Companies according to biotechnology used: Genetic code	Total	32
%Companies according to biotechnology used: Functional units	Fewer than 250 employees	40
%Companies according to biotechnology used: Functional units	250 or more employees	51
%Companies according to biotechnology used: Functional units	Total	41
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Fewer than 250 employees	26
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	250 or more employees	46
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Total	27
%Companies according to biotechnology used: Bioprocesses	Fewer than 250 employees	47
%Companies according to biotechnology used: Bioprocesses	250 or more employees	64
%Companies according to biotechnology used: Bioprocesses	Total	48
%Companies according to biotechnology used: Sub-cellular organisms	Fewer than 250 employees	8
%Companies according to biotechnology used: Sub-cellular organisms	250 or more employees	20
%Companies according to biotechnology used: Sub-cellular organisms	Total	8
%Companies according to biotechnology used: Bio-computing	Fewer than 250 employees	21
%Companies according to biotechnology used: Bio-computing	250 or more employees	31
%Companies according to biotechnology used: Bio-computing	Total	21
%Companies according to biotechnology used: Nanobiotechnology	Fewer than 250 employees	14
%Companies according to biotechnology used: Nanobiotechnology	250 or more employees	18
%Companies according to biotechnology used: Nanobiotechnology	Total	14
%Companies according to biotechnology used: Other	Fewer than 250 employees	13
%Companies according to biotechnology used: Other	250 or more employees	10
%Companies according to biotechnology used: Other	Total	13
Companies in which biotechnology activities are: Main and/or exclusive	Fewer than 250 employees	549
Companies in which biotechnology activities are: Main and/or exclusive	250 or more employees	15
Companies in which biotechnology activities are: Main and/or exclusive	Total	564
Companies in which biotechnology activities are: A secondary line of business	Fewer than 250 employees	193
Companies in which biotechnology activities are: A secondary line of business	250 or more employees	19
Companies in which biotechnology activities are: A secondary line of business	Total	212
Companies in which biotechnology activities are: A tool necessary for production	Fewer than 250 employees	319
Companies in which biotechnology activities are: A tool necessary for production	250 or more employees	38
Companies in which biotechnology activities are: A tool necessary for production	Total	358
%Company by field(s) of ultimate application of biotechnology use: Human Health	Fewer than 250 employees	50
%Company by field(s) of ultimate application of biotechnology use: Human Health	250 or more employees	51
%Company by field(s) of ultimate application of biotechnology use: Human Health	Total	50
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Fewer than 250 employees	20
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	250 or more employees	1
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Total	19
%Company by field(s) of ultimate application of biotechnology use: Food products	Fewer than 250 employees	29
%Company by field(s) of ultimate application of biotechnology use: Food products	250 or more employees	36
%Company by field(s) of ultimate application of biotechnology use: Food products	Total	29
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Fewer than 250 employees	22
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	250 or more employees	18
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Total	21
%Company by field(s) of ultimate application of biotechnology use: Environment	Fewer than 250 employees	13
%Company by field(s) of ultimate application of biotechnology use: Environment	250 or more employees	11
%Company by field(s) of ultimate application of biotechnology use: Environment	Total	13
%Company by field(s) of ultimate application of biotechnology use: Industry	Fewer than 250 employees	14
%Company by field(s) of ultimate application of biotechnology use: Industry	250 or more employees	7
%Company by field(s) of ultimate application of biotechnology use: Industry	Total	13
Personnel in R&D in biotechnology (no. of persons)	Fewer than 250 employees	7.883
Personnel in R&D in biotechnology (no. of persons)	250 or more employees	2.823
Personnel in R&D in biotechnology (no. of persons)	Total	10.706
Personnel in R&D in biotechnology (no. of persons): Researchers	Fewer than 250 employees	4.706
Personnel in R&D in biotechnology (no. of persons): Researchers	250 or more employees	1.521
Personnel in R&D in biotechnology (no. of persons): Researchers	Total	6.227
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Fewer than 250 employees	3.177
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	250 or more employees	1.302
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Total	4.479
Personnel in R&D in biotechnology (no. of persons): women	Fewer than 250 employees	4.068
Personnel in R&D in biotechnology (no. of persons): women	250 or more employees	1.727
Personnel in R&D in biotechnology (no. of persons): women	Total	5.795
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Fewer than 250 employees	2.417
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	250 or more employees	852
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Total	3.269
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Fewer than 250 employees	1.652
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	250 or more employees	875
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Total	2.527
Personnel in R&D in biotechnology (FTE)	Fewer than 250 employees	5.599
Personnel in R&D in biotechnology (FTE)	250 or more employees	2.117,4
Personnel in R&D in biotechnology (FTE)	Total	7.716,4
Personnel in R&D in biotechnology (FTE): Researchers	Fewer than 250 employees	3.511,8
Personnel in R&D in biotechnology (FTE): Researchers	250 or more employees	1.091,3
Personnel in R&D in biotechnology (FTE): Researchers	Total	4.603,1
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Fewer than 250 employees	2.087,2
Personnel in R&D in biotechnology (FTE): Technicians and assistants	250 or more employees	1.026,1
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Total	3.113,3
Personnel in R&D in biotechnology (FTE): women	Fewer than 250 employees	2.969,5
Personnel in R&D in biotechnology (FTE): women	250 or more employees	1.323,4
Personnel in R&D in biotechnology (FTE): women	Total	4.292,9
Personnel in R&D in biotechnology (FTE): (women) Researchers	Fewer than 250 employees	1.832,2
Personnel in R&D in biotechnology (FTE): (women) Researchers	250 or more employees	614,2
Personnel in R&D in biotechnology (FTE): (women) Researchers	Total	2.446,4
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Fewer than 250 employees	1.137,3
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	250 or more employees	709,2
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Total	1.846,5
Internal expenditure on R&D (thousands of euros)	Fewer than 250 employees	452.121
Internal expenditure on R&D (thousands of euros)	250 or more employees	163.932
Internal expenditure on R&D (thousands of euros)	Total	616.053
1) By nature of the expense: Current expenses	Fewer than 250 employees	413.906
1) By nature of the expense: Current expenses	250 or more employees	160.340
1) By nature of the expense: Current expenses	Total	574.245
1.1) Remuneration to researchers	Fewer than 250 employees	160.779
1.1) Remuneration to researchers	250 or more employees	60.962
1.1) Remuneration to researchers	Total	221.741
1.2) Remuneration to technicians and assistants	Fewer than 250 employees	61.960
1.2) Remuneration to technicians and assistants	250 or more employees	40.504
1.2) Remuneration to technicians and assistants	Total	102.464
1.3) Other current expenses	Fewer than 250 employees	191.167
1.3) Other current expenses	250 or more employees	58.874
1.3) Other current expenses	Total	250.041
2) By nature of the expense: Capital expenses	Fewer than 250 employees	38.215
2) By nature of the expense: Capital expenses	250 or more employees	3.593
2) By nature of the expense: Capital expenses	Total	41.808
2.1) Land and buildings	Fewer than 250 employees	4.988
2.1) Land and buildings	250 or more employees	371
2.1) Land and buildings	Total	5.359
2.2) Equipment and instruments	Fewer than 250 employees	26.997
2.2) Equipment and instruments	250 or more employees	2.493
2.2) Equipment and instruments	Total	29.489
2.3) Acquisition of specific R&D software	Fewer than 250 employees	1.716
2.3) Acquisition of specific R&D software	250 or more employees	590
2.3) Acquisition of specific R&D software	Total	2.306
2.4) Otros productos de propiedad intelectual específicos para I+D	Fewer than 250 employees	4.515
2.4) Otros productos de propiedad intelectual específicos para I+D	250 or more employees	139
2.4) Otros productos de propiedad intelectual específicos para I+D	Total	4.654
1) By origin of the funds: National funds	Fewer than 250 employees	388.127
1) By origin of the funds: National funds	250 or more employees	123.833
1) By origin of the funds: National funds	Total	511.960
1.1) Own funds	Fewer than 250 employees	294.928
1.1) Own funds	250 or more employees	87.407
1.1) Own funds	Total	382.335
1.2) From companies	Fewer than 250 employees	29.072
1.2) From companies	250 or more employees	15.952
1.2) From companies	Total	45.024
1.3) Public Administration funds	Fewer than 250 employees	60.976
1.3) Public Administration funds	250 or more employees	11.410
1.3) Public Administration funds	Total	72.387
1.4) From Universities	Fewer than 250 employees	363
1.4) From Universities	250 or more employees	0
1.4) From Universities	Total	363
1.5) From non profit private institutions	Fewer than 250 employees	2.788
1.5) From non profit private institutions	250 or more employees	9.064
1.5) From non profit private institutions	Total	11.851
1) By origin of the funds: Foreign funds	Fewer than 250 employees	63.994
1) By origin of the funds: Foreign funds	250 or more employees	40.100
1) By origin of the funds: Foreign funds	Total	104.093
2.1) From EU programmes	Fewer than 250 employees	18.363
2.1) From EU programmes	250 or more employees	3.462
2.1) From EU programmes	Total	21.825
2.2) Other foreign funds	Fewer than 250 employees	45.631
2.2) Other foreign funds	250 or more employees	36.638
2.2) Other foreign funds	Total	82.269
Purchase of R&D services in biotechnology (thousands of euros)	Fewer than 250 employees	88.908
Purchase of R&D services in biotechnology (thousands of euros)	250 or more employees	55.434
Purchase of R&D services in biotechnology (thousands of euros)	Total	144.342
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Fewer than 250 employees	35.758
Purchase of R&D services in biotechnology (thousands of euros): In Spain	250 or more employees	34.700
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Total	70.458
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Fewer than 250 employees	53.150
Purchase of R&D services in biotechnology (thousands of euros): Abroad	250 or more employees	20.734
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Total	73.885
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Fewer than 250 employees	49
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	250 or more employees	29
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Total	48
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Fewer than 250 employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	250 or more employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Total	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Fewer than 250 employees	15
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	250 or more employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Total	15
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Fewer than 250 employees	12
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Total	12
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Fewer than 250 employees	16
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Total	16
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Fewer than 250 employees	17
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	250 or more employees	10
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Total	16
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Fewer than 250 employees	16
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Total	16
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Fewer than 250 employees	36
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	250 or more employees	35
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Total	36
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Fewer than 250 employees	49
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	250 or more employees	39
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Total	49
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Fewer than 250 employees	18
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Total	18
% Companies that have requested biotechnology patents in Biotechnology	Fewer than 250 employees	16
% Companies that have requested biotechnology patents in Biotechnology	250 or more employees	12
% Companies that have requested biotechnology patents in Biotechnology	Total	16
Number of patents requested	Fewer than 250 employees	570
Number of patents requested	250 or more employees	63
Number of patents requested	Total	633
% Companies with income of an international origin related to biotechnological activities	Fewer than 250 employees	24,2
% Companies with income of an international origin related to biotechnological activities	250 or more employees	20,7
% Companies with income of an international origin related to biotechnological activities	Total	24
% Turnover representing income of an international origin related to biotechnological activities	Fewer than 250 employees	6,1
% Turnover representing income of an international origin related to biotechnological activities	250 or more employees	0,9
% Turnover representing income of an international origin related to biotechnological activities	Total	1,4
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Fewer than 250 employees	37,3
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	250 or more employees	75,7
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Total	57,3
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Fewer than 250 employees	62,7
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	250 or more employees	24,3
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Total	42,7
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Fewer than 250 employees	96,3
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	250 or more employees	69,4
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Total	82,3
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Fewer than 250 employees	2,4
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	250 or more employees	29,4
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Total	16,5
% Income of an international origin related with activities according to the classification: Operating source abroad	Fewer than 250 employees	1,1
% Income of an international origin related with activities according to the classification: Operating source abroad	250 or more employees	0,9
% Income of an international origin related with activities according to the classification: Operating source abroad	Total	1
% Income of an international origin related with activities according to the classification: Other	Fewer than 250 employees	0,2
% Income of an international origin related with activities according to the classification: Other	250 or more employees	0,3
% Income of an international origin related with activities according to the classification: Other	Total	0,3