Main variables	No. of employees	Total
No. of companies carrying out R&D in Biotechnology	Fewer than 250 employees	975
No. of companies carrying out R&D in Biotechnology	250 or more employees	81
No. of companies carrying out R&D in Biotechnology	Total	1.056
%Companies according to biotechnology used: Genetic code	Fewer than 250 employees	35
%Companies according to biotechnology used: Genetic code	250 or more employees	46
%Companies according to biotechnology used: Genetic code	Total	36
%Companies according to biotechnology used: Functional units	Fewer than 250 employees	44
%Companies according to biotechnology used: Functional units	250 or more employees	50
%Companies according to biotechnology used: Functional units	Total	45
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Fewer than 250 employees	26
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	250 or more employees	45
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Total	27
%Companies according to biotechnology used: Bioprocesses	Fewer than 250 employees	45
%Companies according to biotechnology used: Bioprocesses	250 or more employees	66
%Companies according to biotechnology used: Bioprocesses	Total	47
%Companies according to biotechnology used: Sub-cellular organisms	Fewer than 250 employees	8
%Companies according to biotechnology used: Sub-cellular organisms	250 or more employees	15
%Companies according to biotechnology used: Sub-cellular organisms	Total	8
%Companies according to biotechnology used: Bio-computing	Fewer than 250 employees	24
%Companies according to biotechnology used: Bio-computing	250 or more employees	32
%Companies according to biotechnology used: Bio-computing	Total	25
%Companies according to biotechnology used: Nanobiotechnology	Fewer than 250 employees	13
%Companies according to biotechnology used: Nanobiotechnology	250 or more employees	16
%Companies according to biotechnology used: Nanobiotechnology	Total	13
%Companies according to biotechnology used: Other	Fewer than 250 employees	15
%Companies according to biotechnology used: Other	250 or more employees	13
%Companies according to biotechnology used: Other	Total	15
Companies in which biotechnology activities are: Main and/or exclusive	Fewer than 250 employees	538
Companies in which biotechnology activities are: Main and/or exclusive	250 or more employees	12
Companies in which biotechnology activities are: Main and/or exclusive	Total	551
Companies in which biotechnology activities are: A secondary line of business	Fewer than 250 employees	164
Companies in which biotechnology activities are: A secondary line of business	250 or more employees	19
Companies in which biotechnology activities are: A secondary line of business	Total	183
Companies in which biotechnology activities are: A tool necessary for production	Fewer than 250 employees	273
Companies in which biotechnology activities are: A tool necessary for production	250 or more employees	50
Companies in which biotechnology activities are: A tool necessary for production	Total	323
%Company by field(s) of ultimate application of biotechnology use: Human Health	Fewer than 250 employees	49
%Company by field(s) of ultimate application of biotechnology use: Human Health	250 or more employees	52
%Company by field(s) of ultimate application of biotechnology use: Human Health	Total	49
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Fewer than 250 employees	22
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	250 or more employees	3
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Total	20
%Company by field(s) of ultimate application of biotechnology use: Food products	Fewer than 250 employees	30
%Company by field(s) of ultimate application of biotechnology use: Food products	250 or more employees	36
%Company by field(s) of ultimate application of biotechnology use: Food products	Total	30
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Fewer than 250 employees	23
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	250 or more employees	13
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Total	23
%Company by field(s) of ultimate application of biotechnology use: Environment	Fewer than 250 employees	13
%Company by field(s) of ultimate application of biotechnology use: Environment	250 or more employees	17
%Company by field(s) of ultimate application of biotechnology use: Environment	Total	13
%Company by field(s) of ultimate application of biotechnology use: Industry	Fewer than 250 employees	13
%Company by field(s) of ultimate application of biotechnology use: Industry	250 or more employees	7
%Company by field(s) of ultimate application of biotechnology use: Industry	Total	12
Personnel in R&D in biotechnology (no. of persons)	Fewer than 250 employees	7.908
Personnel in R&D in biotechnology (no. of persons)	250 or more employees	2.811
Personnel in R&D in biotechnology (no. of persons)	Total	10.719
Personnel in R&D in biotechnology (no. of persons): Researchers	Fewer than 250 employees	4.660
Personnel in R&D in biotechnology (no. of persons): Researchers	250 or more employees	1.470
Personnel in R&D in biotechnology (no. of persons): Researchers	Total	6.131
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Fewer than 250 employees	3.247
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	250 or more employees	1.341
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Total	4.588
Personnel in R&D in biotechnology (no. of persons): women	Fewer than 250 employees	4.291
Personnel in R&D in biotechnology (no. of persons): women	250 or more employees	1.749
Personnel in R&D in biotechnology (no. of persons): women	Total	6.040
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Fewer than 250 employees	2.520
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	250 or more employees	891
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Total	3.411
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Fewer than 250 employees	1.772
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	250 or more employees	857
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Total	2.629
Personnel in R&D in biotechnology (FTE)	Fewer than 250 employees	5.651,3
Personnel in R&D in biotechnology (FTE)	250 or more employees	2.099,5
Personnel in R&D in biotechnology (FTE)	Total	7.750,8
Personnel in R&D in biotechnology (FTE): Researchers	Fewer than 250 employees	3.461,8
Personnel in R&D in biotechnology (FTE): Researchers	250 or more employees	1.056,3
Personnel in R&D in biotechnology (FTE): Researchers	Total	4.518,1
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Fewer than 250 employees	2.189,4
Personnel in R&D in biotechnology (FTE): Technicians and assistants	250 or more employees	1.043,3
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Total	3.232,7
Personnel in R&D in biotechnology (FTE): women	Fewer than 250 employees	3.133,9
Personnel in R&D in biotechnology (FTE): women	250 or more employees	1.337,5
Personnel in R&D in biotechnology (FTE): women	Total	4.471,4
Personnel in R&D in biotechnology (FTE): (women) Researchers	Fewer than 250 employees	1.912
Personnel in R&D in biotechnology (FTE): (women) Researchers	250 or more employees	650,7
Personnel in R&D in biotechnology (FTE): (women) Researchers	Total	2.562,7
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Fewer than 250 employees	1.221,9
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	250 or more employees	686,8
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Total	1.908,7
Internal expenditure on R&D (thousands of euros)	Fewer than 250 employees	511.004
Internal expenditure on R&D (thousands of euros)	250 or more employees	168.555
Internal expenditure on R&D (thousands of euros)	Total	679.558
1) By nature of the expense: Current expenses	Fewer than 250 employees	470.651
1) By nature of the expense: Current expenses	250 or more employees	163.981
1) By nature of the expense: Current expenses	Total	634.631
1.1) Remuneration to researchers	Fewer than 250 employees	167.208
1.1) Remuneration to researchers	250 or more employees	61.649
1.1) Remuneration to researchers	Total	228.857
1.2) Remuneration to technicians and assistants	Fewer than 250 employees	63.658
1.2) Remuneration to technicians and assistants	250 or more employees	40.840
1.2) Remuneration to technicians and assistants	Total	104.498
1.3) Other current expenses	Fewer than 250 employees	239.785
1.3) Other current expenses	250 or more employees	61.492
1.3) Other current expenses	Total	301.276
2) By nature of the expense: Capital expenses	Fewer than 250 employees	40.353
2) By nature of the expense: Capital expenses	250 or more employees	4.574
2) By nature of the expense: Capital expenses	Total	44.927
2.1) Land and buildings	Fewer than 250 employees	2.519
2.1) Land and buildings	250 or more employees	66
2.1) Land and buildings	Total	2.585
2.2) Equipment and instruments	Fewer than 250 employees	19.828
2.2) Equipment and instruments	250 or more employees	3.741
2.2) Equipment and instruments	Total	23.569
2.3) Acquisition of specific R&D software	Fewer than 250 employees	780
2.3) Acquisition of specific R&D software	250 or more employees	612
2.3) Acquisition of specific R&D software	Total	1.392
2.4) Otros productos de propiedad intelectual específicos para I+D	Fewer than 250 employees	17.226
2.4) Otros productos de propiedad intelectual específicos para I+D	250 or more employees	155
2.4) Otros productos de propiedad intelectual específicos para I+D	Total	17.381
1) By origin of the funds: National funds	Fewer than 250 employees	417.983
1) By origin of the funds: National funds	250 or more employees	138.313
1) By origin of the funds: National funds	Total	556.297
1.1) Own funds	Fewer than 250 employees	301.946
1.1) Own funds	250 or more employees	85.064
1.1) Own funds	Total	387.010
1.2) From companies	Fewer than 250 employees	49.801
1.2) From companies	250 or more employees	36.223
1.2) From companies	Total	86.025
1.3) Public Administration funds	Fewer than 250 employees	61.218
1.3) Public Administration funds	250 or more employees	13.546
1.3) Public Administration funds	Total	74.764
1.4) From Universities	Fewer than 250 employees	408
1.4) From Universities	250 or more employees	0
1.4) From Universities	Total	408
1.5) From non profit private institutions	Fewer than 250 employees	4.610
1.5) From non profit private institutions	250 or more employees	3.480
1.5) From non profit private institutions	Total	8.090
1) By origin of the funds: Foreign funds	Fewer than 250 employees	93.020
1) By origin of the funds: Foreign funds	250 or more employees	30.241
1) By origin of the funds: Foreign funds	Total	123.262
2.1) From EU programmes	Fewer than 250 employees	18.993
2.1) From EU programmes	250 or more employees	6.132
2.1) From EU programmes	Total	25.125
2.2) Other foreign funds	Fewer than 250 employees	74.027
2.2) Other foreign funds	250 or more employees	24.109
2.2) Other foreign funds	Total	98.137
Purchase of R&D services in biotechnology (thousands of euros)	Fewer than 250 employees	86.267
Purchase of R&D services in biotechnology (thousands of euros)	250 or more employees	61.292
Purchase of R&D services in biotechnology (thousands of euros)	Total	147.558
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Fewer than 250 employees	26.503
Purchase of R&D services in biotechnology (thousands of euros): In Spain	250 or more employees	50.373
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Total	76.875
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Fewer than 250 employees	59.764
Purchase of R&D services in biotechnology (thousands of euros): Abroad	250 or more employees	10.919
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Total	70.683
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Fewer than 250 employees	50
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	250 or more employees	25
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Total	49
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Fewer than 250 employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	250 or more employees	11
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Total	14
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Fewer than 250 employees	16
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	250 or more employees	15
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Total	16
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Fewer than 250 employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	250 or more employees	15
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Total	13
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Fewer than 250 employees	18
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	250 or more employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Total	18
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Fewer than 250 employees	19
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	250 or more employees	8
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Total	18
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Fewer than 250 employees	17
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Total	17
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Fewer than 250 employees	38
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	250 or more employees	30
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Total	37
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Fewer than 250 employees	52
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	250 or more employees	40
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Total	51
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Fewer than 250 employees	18
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	250 or more employees	14
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Total	18
% Companies that have requested biotechnology patents in Biotechnology	Fewer than 250 employees	15
% Companies that have requested biotechnology patents in Biotechnology	250 or more employees	16
% Companies that have requested biotechnology patents in Biotechnology	Total	16
Number of patents requested	Fewer than 250 employees	602
Number of patents requested	250 or more employees	144
Number of patents requested	Total	746
% Companies with income of an international origin related to biotechnological activities	Fewer than 250 employees	23,9
% Companies with income of an international origin related to biotechnological activities	250 or more employees	16
% Companies with income of an international origin related to biotechnological activities	Total	23,3
% Turnover representing income of an international origin related to biotechnological activities	Fewer than 250 employees	5,7
% Turnover representing income of an international origin related to biotechnological activities	250 or more employees	0,7
% Turnover representing income of an international origin related to biotechnological activities	Total	1,2
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Fewer than 250 employees	49,3
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	250 or more employees	69,7
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Total	60,4
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Fewer than 250 employees	50,7
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	250 or more employees	30,3
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Total	39,6
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Fewer than 250 employees	92,6
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	250 or more employees	71,2
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Total	80,9
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Fewer than 250 employees	5,5
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	250 or more employees	27,9
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Total	17,8
% Income of an international origin related with activities according to the classification: Operating source abroad	Fewer than 250 employees	1,9
% Income of an international origin related with activities according to the classification: Operating source abroad	250 or more employees	0,8
% Income of an international origin related with activities according to the classification: Operating source abroad	Total	1,3
% Income of an international origin related with activities according to the classification: Other	Fewer than 250 employees	0,1
% Income of an international origin related with activities according to the classification: Other	250 or more employees	.
% Income of an international origin related with activities according to the classification: Other	Total	0,1