Main variables Branches of activity Total No. of companies carrying out R&D in Biotechnology Total Companies 1.233 No. of companies carrying out R&D in Biotechnology Services 740 No. of companies carrying out R&D in Biotechnology Industry and Construction 405 No. of companies carrying out R&D in Biotechnology Agriculture 89 %Companies according to biotechnology used: Genetic code Total Companies 31,7 %Companies according to biotechnology used: Genetic code Services 41,6 %Companies according to biotechnology used: Genetic code Industry and Construction 15,1 %Companies according to biotechnology used: Genetic code Agriculture 24,8 %Companies according to biotechnology used: Functional units Total Companies 38,5 %Companies according to biotechnology used: Functional units Services 43,6 %Companies according to biotechnology used: Functional units Industry and Construction 32,2 %Companies according to biotechnology used: Functional units Agriculture 25,2 %Companies according to biotechnology used: Cellular and tissue culturing and engineering Total Companies 22,8 %Companies according to biotechnology used: Cellular and tissue culturing and engineering Services 27,7 %Companies according to biotechnology used: Cellular and tissue culturing and engineering Industry and Construction 14,6 %Companies according to biotechnology used: Cellular and tissue culturing and engineering Agriculture 19 %Companies according to biotechnology used: Bioprocesses Total Companies 53,4 %Companies according to biotechnology used: Bioprocesses Services 43,1 %Companies according to biotechnology used: Bioprocesses Industry and Construction 76,8 %Companies according to biotechnology used: Bioprocesses Agriculture 32,3 %Companies according to biotechnology used: Sub-cellular organisms Total Companies 8,6 %Companies according to biotechnology used: Sub-cellular organisms Services 11,9 %Companies according to biotechnology used: Sub-cellular organisms Industry and Construction 4,6 %Companies according to biotechnology used: Sub-cellular organisms Agriculture 0 %Companies according to biotechnology used: Bio-computing Total Companies 22,3 %Companies according to biotechnology used: Bio-computing Services 31 %Companies according to biotechnology used: Bio-computing Industry and Construction 9,6 %Companies according to biotechnology used: Bio-computing Agriculture 7,1 %Companies according to biotechnology used: Nanobiotechnology Total Companies 10,6 %Companies according to biotechnology used: Nanobiotechnology Services 13,8 %Companies according to biotechnology used: Nanobiotechnology Industry and Construction 6,9 %Companies according to biotechnology used: Nanobiotechnology Agriculture 1,1 %Companies according to biotechnology used: Other Total Companies 14,2 %Companies according to biotechnology used: Other Services 15,7 %Companies according to biotechnology used: Other Industry and Construction 7,6 %Companies according to biotechnology used: Other Agriculture 31,7 Companies in which biotechnology activities are: Main and/or exclusive Total Companies 615 Companies in which biotechnology activities are: Main and/or exclusive Services 485 Companies in which biotechnology activities are: Main and/or exclusive Industry and Construction 113 Companies in which biotechnology activities are: Main and/or exclusive Agriculture 17 Companies in which biotechnology activities are: A secondary line of business Total Companies 178 Companies in which biotechnology activities are: A secondary line of business Services 85 Companies in which biotechnology activities are: A secondary line of business Industry and Construction 79 Companies in which biotechnology activities are: A secondary line of business Agriculture 15 Companies in which biotechnology activities are: A tool necessary for production Total Companies 440 Companies in which biotechnology activities are: A tool necessary for production Services 170 Companies in which biotechnology activities are: A tool necessary for production Industry and Construction 213 Companies in which biotechnology activities are: A tool necessary for production Agriculture 57 %Company by field(s) of ultimate application of biotechnology use: Human Health Total Companies 46,3 %Company by field(s) of ultimate application of biotechnology use: Human Health Services 63,5 %Company by field(s) of ultimate application of biotechnology use: Human Health Industry and Construction 24,4 %Company by field(s) of ultimate application of biotechnology use: Human Health Agriculture 2,3 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture Total Companies 16,2 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture Services 17,8 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture Industry and Construction 11,8 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture Agriculture 23,5 %Company by field(s) of ultimate application of biotechnology use: Food products Total Companies 32 %Company by field(s) of ultimate application of biotechnology use: Food products Services 22,4 %Company by field(s) of ultimate application of biotechnology use: Food products Industry and Construction 50 %Company by field(s) of ultimate application of biotechnology use: Food products Agriculture 30 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production Total Companies 24,6 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production Services 23,1 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production Industry and Construction 18,7 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production Agriculture 63,4 %Company by field(s) of ultimate application of biotechnology use: Environment Total Companies 15,5 %Company by field(s) of ultimate application of biotechnology use: Environment Services 15 %Company by field(s) of ultimate application of biotechnology use: Environment Industry and Construction 15,5 %Company by field(s) of ultimate application of biotechnology use: Environment Agriculture 19,7 %Company by field(s) of ultimate application of biotechnology use: Industry Total Companies 12,9 %Company by field(s) of ultimate application of biotechnology use: Industry Services 13,5 %Company by field(s) of ultimate application of biotechnology use: Industry Industry and Construction 14,1 %Company by field(s) of ultimate application of biotechnology use: Industry Agriculture 2,3 Personnel in R&D in biotechnology (no. of persons) Total Companies 13.444 Personnel in R&D in biotechnology (no. of persons) Services 8.462 Personnel in R&D in biotechnology (no. of persons) Industry and Construction 4.143 Personnel in R&D in biotechnology (no. of persons) Agriculture 840 Personnel in R&D in biotechnology (no. of persons): Researchers Total Companies 7.378 Personnel in R&D in biotechnology (no. of persons): Researchers Services 5.167 Personnel in R&D in biotechnology (no. of persons): Researchers Industry and Construction 1.974 Personnel in R&D in biotechnology (no. of persons): Researchers Agriculture 237 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants Total Companies 6.066 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants Services 3.295 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants Industry and Construction 2.169 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants Agriculture 603 Personnel in R&D in biotechnology (no. of persons): women Total Companies 7.501 Personnel in R&D in biotechnology (no. of persons): women Services 4.900 Personnel in R&D in biotechnology (no. of persons): women Industry and Construction 2.238 Personnel in R&D in biotechnology (no. of persons): women Agriculture 363 Personnel in R&D in biotechnology (no. of persons): (women) Researchers Total Companies 4.052 Personnel in R&D in biotechnology (no. of persons): (women) Researchers Services 2.875 Personnel in R&D in biotechnology (no. of persons): (women) Researchers Industry and Construction 1.070 Personnel in R&D in biotechnology (no. of persons): (women) Researchers Agriculture 106 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants Total Companies 3.450 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants Services 2.025 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants Industry and Construction 1.168 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants Agriculture 257 Personnel in R&D in biotechnology (FTE) Total Companies 9.401,9 Personnel in R&D in biotechnology (FTE) Services 5.991,3 Personnel in R&D in biotechnology (FTE) Industry and Construction 2.869,8 Personnel in R&D in biotechnology (FTE) Agriculture 540,9 Personnel in R&D in biotechnology (FTE): Researchers Total Companies 5.398,3 Personnel in R&D in biotechnology (FTE): Researchers Services 3.774,1 Personnel in R&D in biotechnology (FTE): Researchers Industry and Construction 1.455,1 Personnel in R&D in biotechnology (FTE): Researchers Agriculture 169,2 Personnel in R&D in biotechnology (FTE): Technicians and assistants Total Companies 4.003,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants Services 2.217,2 Personnel in R&D in biotechnology (FTE): Technicians and assistants Industry and Construction 1.414,7 Personnel in R&D in biotechnology (FTE): Technicians and assistants Agriculture 371,7 Personnel in R&D in biotechnology (FTE): women Total Companies 5.426,2 Personnel in R&D in biotechnology (FTE): women Services 3.510,7 Personnel in R&D in biotechnology (FTE): women Industry and Construction 1.654,8 Personnel in R&D in biotechnology (FTE): women Agriculture 260,7 Personnel in R&D in biotechnology (FTE): (women) Researchers Total Companies 3.016,4 Personnel in R&D in biotechnology (FTE): (women) Researchers Services 2.104,1 Personnel in R&D in biotechnology (FTE): (women) Researchers Industry and Construction 830,3 Personnel in R&D in biotechnology (FTE): (women) Researchers Agriculture 82,1 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants Total Companies 2.409,8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants Services 1.406,6 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants Industry and Construction 824,5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants Agriculture 178,7 Internal expenditure on R&D (thousands of euros) Total Companies 897.333 Internal expenditure on R&D (thousands of euros) Services 545.374 Internal expenditure on R&D (thousands of euros) Industry and Construction 308.398 Internal expenditure on R&D (thousands of euros) Agriculture 43.561 1) By nature of the expense: Current expenses Total Companies 817.409 1) By nature of the expense: Current expenses Services 495.422 1) By nature of the expense: Current expenses Industry and Construction 283.561 1) By nature of the expense: Current expenses Agriculture 38.426 1.1) Remuneration to researchers Total Companies 295.705 1.1) Remuneration to researchers Services 177.158 1.1) Remuneration to researchers Industry and Construction 109.976 1.1) Remuneration to researchers Agriculture 8.570 1.2) Remuneration to technicians and assistants Total Companies 156.853 1.2) Remuneration to technicians and assistants Services 84.448 1.2) Remuneration to technicians and assistants Industry and Construction 62.043 1.2) Remuneration to technicians and assistants Agriculture 10.362 1.3) Other current expenses Total Companies 364.852 1.3) Other current expenses Services 233.816 1.3) Other current expenses Industry and Construction 111.542 1.3) Other current expenses Agriculture 19.494 2) By nature of the expense: Capital expenses Total Companies 79.924 2) By nature of the expense: Capital expenses Services 49.952 2) By nature of the expense: Capital expenses Industry and Construction 24.837 2) By nature of the expense: Capital expenses Agriculture 5.135 2.1) Land and buildings Total Companies 10.272 2.1) Land and buildings Services 5.381 2.1) Land and buildings Industry and Construction 2.529 2.1) Land and buildings Agriculture 2.362 2.2) Equipment and instruments Total Companies 56.609 2.2) Equipment and instruments Services 35.410 2.2) Equipment and instruments Industry and Construction 19.076 2.2) Equipment and instruments Agriculture 2.123 2.3) Acquisition of specific R&D software Total Companies 4.839 2.3) Acquisition of specific R&D software Services 2.768 2.3) Acquisition of specific R&D software Industry and Construction 1.974 2.3) Acquisition of specific R&D software Agriculture 97 2.4) Otros productos de propiedad intelectual específicos para I+D Total Companies 8.203 2.4) Otros productos de propiedad intelectual específicos para I+D Services 6.393 2.4) Otros productos de propiedad intelectual específicos para I+D Industry and Construction 1.257 2.4) Otros productos de propiedad intelectual específicos para I+D Agriculture 552 1.1) By origin of the funds: Own funds Total Companies 613.097 1.1) By origin of the funds: Own funds Services 312.617 1.1) By origin of the funds: Own funds Industry and Construction 260.467 1.1) By origin of the funds: Own funds Agriculture 40.014 1.2) By origin of the funds: From companies Total Companies 86.085 1.2) By origin of the funds: From companies Services 76.374 1.2) By origin of the funds: From companies Industry and Construction 9.711 1.2) By origin of the funds: From companies Agriculture 0 1.3) By origin of the funds: Public Administration funds Total Companies 92.140 1.3) By origin of the funds: Public Administration funds Services 79.925 1.3) By origin of the funds: Public Administration funds Industry and Construction 10.827 1.3) By origin of the funds: Public Administration funds Agriculture 1.388 1.4) By origin of the funds: From Universities Total Companies 853 1.4) By origin of the funds: From Universities Services 853 1.4) By origin of the funds: From Universities Industry and Construction 0 1.4) By origin of the funds: From Universities Agriculture 0 1.5) By origin of the funds: From non profit private institutions Total Companies 4.682 1.5) By origin of the funds: From non profit private institutions Services 4.682 1.5) By origin of the funds: From non profit private institutions Industry and Construction 0 1.5) By origin of the funds: From non profit private institutions Agriculture 0 1.6) By origin of the funds: Foreign funds Total Companies 100.476 1.6) By origin of the funds: Foreign funds Services 70.924 1.6) By origin of the funds: Foreign funds Industry and Construction 27.393 1.6) By origin of the funds: Foreign funds Agriculture 2.159 Purchase of R&D services in biotechnology (thousands of euros) Total Companies 85.011 Purchase of R&D services in biotechnology (thousands of euros) Services 43.595 Purchase of R&D services in biotechnology (thousands of euros) Industry and Construction 40.577 Purchase of R&D services in biotechnology (thousands of euros) Agriculture 839 Purchase of R&D services in biotechnology (thousands of euros): In Spain Total Companies 54.243 Purchase of R&D services in biotechnology (thousands of euros): In Spain Services 18.614 Purchase of R&D services in biotechnology (thousands of euros): In Spain Industry and Construction 34.957 Purchase of R&D services in biotechnology (thousands of euros): In Spain Agriculture 672 Purchase of R&D services in biotechnology (thousands of euros): Abroad Total Companies 30.768 Purchase of R&D services in biotechnology (thousands of euros): Abroad Services 24.981 Purchase of R&D services in biotechnology (thousands of euros): Abroad Industry and Construction 5.620 Purchase of R&D services in biotechnology (thousands of euros): Abroad Agriculture 168 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital Total Companies 39,2 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital Services 49,7 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital Industry and Construction 23,8 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital Agriculture 22,7 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information Total Companies 11,7 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information Services 11,7 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information Industry and Construction 11,5 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information Agriculture 12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources Total Companies 12,5 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources Services 13,6 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources Industry and Construction 10,5 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources Agriculture 12,9 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain Total Companies 10,9 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain Services 11,8 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain Industry and Construction 9,1 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain Agriculture 11,3 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets Total Companies 14,3 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets Services 17,6 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets Industry and Construction 8,5 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets Agriculture 13 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels Total Companies 16,5 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels Services 20,8 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels Industry and Construction 9,3 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels Agriculture 13,6 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception Total Companies 15 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception Services 17,7 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception Industry and Construction 9,7 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception Agriculture 17 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements Total Companies 36 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements Services 40 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements Industry and Construction 30 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements Agriculture 32 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost Total Companies 46,7 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost Services 50,9 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost Industry and Construction 39,7 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost Agriculture 43,2 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting Total Companies 19 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting Services 21,6 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting Industry and Construction 14,2 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting Agriculture 19,5 % Companies that have requested biotechnology patents in Biotechnology Total Companies 17,3 % Companies that have requested biotechnology patents in Biotechnology Services 22,1 % Companies that have requested biotechnology patents in Biotechnology Industry and Construction 10,4 % Companies that have requested biotechnology patents in Biotechnology Agriculture 9,4 Number of patents requested Total Companies 681 Number of patents requested Services 528 Number of patents requested Industry and Construction 119 Number of patents requested Agriculture 34 % Companies with income of an international origin related to biotechnological activities Total Companies 23 % Companies with income of an international origin related to biotechnological activities Services 25,3 % Companies with income of an international origin related to biotechnological activities Industry and Construction 22,1 % Companies with income of an international origin related to biotechnological activities Agriculture 8,6 % Turnover representing income of an international origin related to biotechnological activities Total Companies 1,6 % Turnover representing income of an international origin related to biotechnological activities Services 5,1 % Turnover representing income of an international origin related to biotechnological activities Industry and Construction 1,3 % Turnover representing income of an international origin related to biotechnological activities Agriculture 1,2 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU Total Companies 55,9 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU Services 30,1 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU Industry and Construction 65,4 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU Agriculture 78,2 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries Total Companies 44,1 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries Services 69,9 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries Industry and Construction 34,6 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries Agriculture 21,8 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services Total Companies 83,9 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services Services 93,7 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services Industry and Construction 79,9 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services Agriculture 90 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Total Companies 14,7 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Services 2 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Industry and Construction 20 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Agriculture 0 % Income of an international origin related with activities according to the classification: Operating source abroad Total Companies 0,8 % Income of an international origin related with activities according to the classification: Operating source abroad Services 2,7 % Income of an international origin related with activities according to the classification: Operating source abroad Industry and Construction 0 % Income of an international origin related with activities according to the classification: Operating source abroad Agriculture 0 % Income of an international origin related with activities according to the classification: Other Total Companies 0,6 % Income of an international origin related with activities according to the classification: Other Services 1,5 % Income of an international origin related with activities according to the classification: Other Industry and Construction 0 % Income of an international origin related with activities according to the classification: Other Agriculture 10