Main variables	Fields of operation	Total
Companies that perform R+D in Biotechnology	Total 2020	1.430
Companies that perform R+D in Biotechnology	Companies	1.233
Companies that perform R+D in Biotechnology	P.A.	118
Companies that perform R+D in Biotechnology	Higher Education	67
Companies that perform R+D in Biotechnology	PNPI	12
%Companies according to biotechnology used: Genetic code	Total 2020	39,1
%Companies according to biotechnology used: Genetic code	Companies	31,7
%Companies according to biotechnology used: Genetic code	P.A.	89
%Companies according to biotechnology used: Genetic code	Higher Education	86,6
%Companies according to biotechnology used: Genetic code	PNPI	41,7
%Companies according to biotechnology used: Functional Companies	Total 2020	45,2
%Companies according to biotechnology used: Functional Companies	Companies	38,5
%Companies according to biotechnology used: Functional Companies	P.A.	88,1
%Companies according to biotechnology used: Functional Companies	Higher Education	91
%Companies according to biotechnology used: Functional Companies	PNPI	58,3
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Total 2020	30,1
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Companies	22,8
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	P.A.	73,7
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Higher Education	80,6
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	PNPI	75
%Companies according to biotechnology used: Bioprocesses	Total 2020	55,7
%Companies according to biotechnology used: Bioprocesses	Companies	53,4
%Companies according to biotechnology used: Bioprocesses	P.A.	57,6
%Companies according to biotechnology used: Bioprocesses	Higher Education	94
%Companies according to biotechnology used: Bioprocesses	PNPI	58,3
%Companies according to biotechnology used: Sub-cellular organisms	Total 2020	15,8
%Companies according to biotechnology used: Sub-cellular organisms	Companies	8,6
%Companies according to biotechnology used: Sub-cellular organisms	P.A.	55,9
%Companies according to biotechnology used: Sub-cellular organisms	Higher Education	74,6
%Companies according to biotechnology used: Sub-cellular organisms	PNPI	33,3
%Companies according to biotechnology used: Bio-computing	Total 2020	29,2
%Companies according to biotechnology used: Bio-computing	Companies	22,3
%Companies according to biotechnology used: Bio-computing	P.A.	71,2
%Companies according to biotechnology used: Bio-computing	Higher Education	85,1
%Companies according to biotechnology used: Bio-computing	PNPI	16,7
%Companies according to biotechnology used: Nanobiotechnology	Total 2020	16,6
%Companies according to biotechnology used: Nanobiotechnology	Companies	10,6
%Companies according to biotechnology used: Nanobiotechnology	P.A.	50
%Companies according to biotechnology used: Nanobiotechnology	Higher Education	68,7
%Companies according to biotechnology used: Nanobiotechnology	PNPI	8,3
%Companies according to biotechnology used: Other	Total 2020	12,7
%Companies according to biotechnology used: Other	Companies	14,2
%Companies according to biotechnology used: Other	P.A.	1,7
%Companies according to biotechnology used: Other	Higher Education	7,5
%Companies according to biotechnology used: Other	PNPI	0
Companies in which biotechnology activities are:  Main and/or exclusive	Total 2020	653
Companies in which biotechnology activities are:  Main and/or exclusive	Companies	615
Companies in which biotechnology activities are:  Main and/or exclusive	P.A.	29
Companies in which biotechnology activities are:  Main and/or exclusive	Higher Education	2
Companies in which biotechnology activities are:  Main and/or exclusive	PNPI	7
Companies in which biotechnology activities are: A secondary line of business	Total 2020	262
Companies in which biotechnology activities are: A secondary line of business	Companies	178
Companies in which biotechnology activities are: A secondary line of business	P.A.	35
Companies in which biotechnology activities are: A secondary line of business	Higher Education	48
Companies in which biotechnology activities are: A secondary line of business	PNPI	1
Companies in which biotechnology activities are: A tool necessary for production	Total 2020	515
Companies in which biotechnology activities are: A tool necessary for production	Companies	440
Companies in which biotechnology activities are: A tool necessary for production	P.A.	54
Companies in which biotechnology activities are: A tool necessary for production	Higher Education	17
Companies in which biotechnology activities are: A tool necessary for production	PNPI	4
%Companies by field(s) of ultimate application of biotechnology use: Human health	Total 2020	51
%Companies by field(s) of ultimate application of biotechnology use: Human health	Companies	46
%Companies by field(s) of ultimate application of biotechnology use: Human health	P.A.	77
%Companies by field(s) of ultimate application of biotechnology use: Human health	Higher Education	91
%Companies by field(s) of ultimate application of biotechnology use: Human health	PNPI	67
%Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Total 2020	19
%Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Companies	16
%Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	P.A.	19
%Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Higher Education	70
%Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	PNPI	25
%Companies by field(s) of ultimate application of biotechnology use: Food products	Total 2020	33
%Companies by field(s) of ultimate application of biotechnology use: Food products	Companies	32
%Companies by field(s) of ultimate application of biotechnology use: Food products	P.A.	23
%Companies by field(s) of ultimate application of biotechnology use: Food products	Higher Education	79
%Companies by field(s) of ultimate application of biotechnology use: Food products	PNPI	0
%Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:	Total 2020	27
%Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:	Companies	25
%Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:	P.A.	23
%Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:	Higher Education	73
%Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:	PNPI	33
%Companies by field(s) of ultimate application of biotechnology use: Environment	Total 2020	19
%Companies by field(s) of ultimate application of biotechnology use: Environment	Companies	16
%Companies by field(s) of ultimate application of biotechnology use: Environment	P.A.	23
%Companies by field(s) of ultimate application of biotechnology use: Environment	Higher Education	76
%Companies by field(s) of ultimate application of biotechnology use: Environment	PNPI	8
%Companies by field(s) of ultimate application of biotechnology use: Industry	Total 2020	16
%Companies by field(s) of ultimate application of biotechnology use: Industry	Companies	13
%Companies by field(s) of ultimate application of biotechnology use: Industry	P.A.	14
%Companies by field(s) of ultimate application of biotechnology use: Industry	Higher Education	70
%Companies by field(s) of ultimate application of biotechnology use: Industry	PNPI	8
Personnel in R&D in biotechnology (no. of persons)	Total 2020	43.568
Personnel in R&D in biotechnology (no. of persons)	Companies	13.444
Personnel in R&D in biotechnology (no. of persons)	P.A.	14.558
Personnel in R&D in biotechnology (no. of persons)	Higher Education	15.422
Personnel in R&D in biotechnology (no. of persons)	PNPI	144
Personnel in R&D in biotechnology (no. of persons): Researchers	Total 2020	28.824
Personnel in R&D in biotechnology (no. of persons): Researchers	Companies	7.378
Personnel in R&D in biotechnology (no. of persons): Researchers	P.A.	8.979
Personnel in R&D in biotechnology (no. of persons): Researchers	Higher Education	12.379
Personnel in R&D in biotechnology (no. of persons): Researchers	PNPI	88
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Total 2020	14.744
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Companies	6.066
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	P.A.	5.579
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Higher Education	3.043
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	PNPI	56
Personnel in R&D in biotechnology (no. of persons): women	Total 2020	24.402
Personnel in R&D in biotechnology (no. of persons): women	Companies	7.501
Personnel in R&D in biotechnology (no. of persons): women	P.A.	9.115
Personnel in R&D in biotechnology (no. of persons): women	Higher Education	7.689
Personnel in R&D in biotechnology (no. of persons): women	PNPI	97
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Total 2020	15.288
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Companies	4.052
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	P.A.	5.262
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Higher Education	5.916
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	PNPI	58
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Total 2020	9.115
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Companies	3.450
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	P.A.	3.853
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Higher Education	1.773
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	PNPI	39
Personnel in R&D in biotechnology (FTE)	Total 2020	30.003,8
Personnel in R&D in biotechnology (FTE)	Companies	9.401,9
Personnel in R&D in biotechnology (FTE)	P.A.	10.846,1
Personnel in R&D in biotechnology (FTE)	Higher Education	9.663,9
Personnel in R&D in biotechnology (FTE)	PNPI	91,9
Personnel in R&D in biotechnology (FTE): Researchers	Total 2020	19.421,7
Personnel in R&D in biotechnology (FTE): Researchers	Companies	5.398,3
Personnel in R&D in biotechnology (FTE): Researchers	P.A.	6.270,9
Personnel in R&D in biotechnology (FTE): Researchers	Higher Education	7.692,1
Personnel in R&D in biotechnology (FTE): Researchers	PNPI	60,4
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Total 2020	10.582,1
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Companies	4.003,6
Personnel in R&D in biotechnology (FTE): Technicians and assistants	P.A.	4.575,2
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Higher Education	1.971,8
Personnel in R&D in biotechnology (FTE): Technicians and assistants	PNPI	31,5
Personnel in R&D in biotechnology (FTE): women	Total 2020	17.268,4
Personnel in R&D in biotechnology (FTE): women	Companies	5.426,2
Personnel in R&D in biotechnology (FTE): women	P.A.	6.853,1
Personnel in R&D in biotechnology (FTE): women	Higher Education	4.923,3
Personnel in R&D in biotechnology (FTE): women	PNPI	65,8
Personnel in R&D in biotechnology (FTE): (women) Researchers	Total 2020	10.512,7
Personnel in R&D in biotechnology (FTE): (women) Researchers	Companies	3.016,4
Personnel in R&D in biotechnology (FTE): (women) Researchers	P.A.	3.680,8
Personnel in R&D in biotechnology (FTE): (women) Researchers	Higher Education	3.774,1
Personnel in R&D in biotechnology (FTE): (women) Researchers	PNPI	41,4
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Total 2020	6.755,7
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Companies	2.409,8
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	P.A.	3.172,3
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Higher Education	1.149,2
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	PNPI	24,4
Internal expenditure on R&D (thousands of euros)	Total 2020	2.059.394
Internal expenditure on R&D (thousands of euros)	Companies	897.333
Internal expenditure on R&D (thousands of euros)	P.A.	678.685
Internal expenditure on R&D (thousands of euros)	Higher Education	477.628
Internal expenditure on R&D (thousands of euros)	PNPI	5.748
1) By nature of the expense: Current expenses	Total 2020	1.896.836
1) By nature of the expense: Current expenses	Companies	817.409
1) By nature of the expense: Current expenses	P.A.	632.188
1) By nature of the expense: Current expenses	Higher Education	441.712
1) By nature of the expense: Current expenses	PNPI	5.526
1.1) Remuneration to researchers	Total 2020	815.653
1.1) Remuneration to researchers	Companies	295.705
1.1) Remuneration to researchers	P.A.	238.938
1.1) Remuneration to researchers	Higher Education	279.152
1.1) Remuneration to researchers	PNPI	1.859
1.2) Remuneration to technicians and assistants	Total 2020	346.532
1.2) Remuneration to technicians and assistants	Companies	156.853
1.2) Remuneration to technicians and assistants	P.A.	127.778
1.2) Remuneration to technicians and assistants	Higher Education	61.050
1.2) Remuneration to technicians and assistants	PNPI	851
1.3) Other current expenses	Total 2020	734.651
1.3) Other current expenses	Companies	364.852
1.3) Other current expenses	P.A.	265.472
1.3) Other current expenses	Higher Education	101.510
1.3) Other current expenses	PNPI	2.817
2) By nature of the expense: Capital expenses	Total 2020	162.558
2) By nature of the expense: Capital expenses	Companies	79.924
2) By nature of the expense: Capital expenses	P.A.	46.497
2) By nature of the expense: Capital expenses	Higher Education	35.916
2) By nature of the expense: Capital expenses	PNPI	221
2.1) Land and buildings	Total 2020	21.618
2.1) Land and buildings	Companies	10.272
2.1) Land and buildings	P.A.	4.863
2.1) Land and buildings	Higher Education	6.483
2.1) Land and buildings	PNPI	0
2.2) Equipment and instruments	Total 2020	125.071
2.2) Equipment and instruments	Companies	56.609
2.2) Equipment and instruments	P.A.	40.467
2.2) Equipment and instruments	Higher Education	27.780
2.2) Equipment and instruments	PNPI	216
2.3) Acquisition of specific R+D software	Total 2020	7.349
2.3) Acquisition of specific R+D software	Companies	4.839
2.3) Acquisition of specific R+D software	P.A.	969
2.3) Acquisition of specific R+D software	Higher Education	1.541
2.3) Acquisition of specific R+D software	PNPI	1
2.4) Otros productos de propiedad intelectual específicos para I+D	Total 2020	8.519
2.4) Otros productos de propiedad intelectual específicos para I+D	Companies	8.203
2.4) Otros productos de propiedad intelectual específicos para I+D	P.A.	199
2.4) Otros productos de propiedad intelectual específicos para I+D	Higher Education	112
2.4) Otros productos de propiedad intelectual específicos para I+D	PNPI	5
1.1) By origin of the funds: Own funds	Total 2020	772.786
1.1) By origin of the funds: Own funds	Companies	613.097
1.1) By origin of the funds: Own funds	P.A.	68.653
1.1) By origin of the funds: Own funds	Higher Education	88.724
1.1) By origin of the funds: Own funds	PNPI	2.311
1.2) By origin of the funds: From companies	Total 2020	222.014
1.2) By origin of the funds: From companies	Companies	86.085
1.2) By origin of the funds: From companies	P.A.	110.014
1.2) By origin of the funds: From companies	Higher Education	25.119
1.2) By origin of the funds: From companies	PNPI	796
1.3) By origin of the funds: Public Administration funds	Total 2020	824.067
1.3) By origin of the funds: Public Administration funds	Companies	92.140
1.3) By origin of the funds: Public Administration funds	P.A.	416.365
1.3) By origin of the funds: Public Administration funds	Higher Education	314.573
1.3) By origin of the funds: Public Administration funds	PNPI	989
1.4) By origin of the funds: From Universities	Total 2020	6.337
1.4) By origin of the funds: From Universities	Companies	853
1.4) By origin of the funds: From Universities	P.A.	1.238
1.4) By origin of the funds: From Universities	Higher Education	4.246
1.4) By origin of the funds: From Universities	PNPI	0
1.5) By origin of the funds: From non profit private institutions	Total 2020	29.754
1.5) By origin of the funds: From non profit private institutions	Companies	4.682
1.5) By origin of the funds: From non profit private institutions	P.A.	15.618
1.5) By origin of the funds: From non profit private institutions	Higher Education	8.422
1.5) By origin of the funds: From non profit private institutions	PNPI	1.032
1.6) By origin of the funds: Foreign funds	Total 2020	204.436
1.6) By origin of the funds: Foreign funds	Companies	100.476
1.6) By origin of the funds: Foreign funds	P.A.	66.798
1.6) By origin of the funds: Foreign funds	Higher Education	36.544
1.6) By origin of the funds: Foreign funds	PNPI	619
Purchase of services R & D in Biotechnology to (thousands of euros)	Total 2020	114.577
Purchase of services R & D in Biotechnology to (thousands of euros)	Companies	85.011
Purchase of services R & D in Biotechnology to (thousands of euros)	P.A.	21.442
Purchase of services R & D in Biotechnology to (thousands of euros)	Higher Education	7.429
Purchase of services R & D in Biotechnology to (thousands of euros)	PNPI	695
Purchase of services R & D in Biotechnology to (thousands of euros): in Spain	Total 2020	81.403
Purchase of services R & D in Biotechnology to (thousands of euros): in Spain	Companies	54.243
Purchase of services R & D in Biotechnology to (thousands of euros): in Spain	P.A.	19.374
Purchase of services R & D in Biotechnology to (thousands of euros): in Spain	Higher Education	7.134
Purchase of services R & D in Biotechnology to (thousands of euros): in Spain	PNPI	652
Purchase of services R & D in Biotechnology to (thousands of euros): Abroad	Total 2020	33.174
Purchase of services R & D in Biotechnology to (thousands of euros): Abroad	Companies	30.768
Purchase of services R & D in Biotechnology to (thousands of euros): Abroad	P.A.	2.068
Purchase of services R & D in Biotechnology to (thousands of euros): Abroad	Higher Education	294
Purchase of services R & D in Biotechnology to (thousands of euros): Abroad	PNPI	43
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Total 2020	42,2
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Companies	39,2
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	P.A.	61
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Higher Education	58,2
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	PNPI	75
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Total 2020	10,9
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Companies	11,7
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	P.A.	3,4
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Higher Education	10,4
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	PNPI	8,3
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Total 2020	16,2
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Companies	12,5
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	P.A.	41,5
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Higher Education	38,8
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	PNPI	25
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Total 2020	13,6
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Companies	10,9
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	P.A.	29,7
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Higher Education	34,3
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	PNPI	16,7
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Total 2020	17,1
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Companies	14,3
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	P.A.	31,4
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Higher Education	41,8
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	PNPI	25
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels	Total 2020	19
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels	Companies	17
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels	P.A.	29
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels	Higher Education	40
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels	PNPI	25
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Total 2020	14,5
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Companies	15
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	P.A.	9,3
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Higher Education	10,4
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	PNPI	33,3
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Total 2020	36
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Companies	36
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	P.A.	37
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Higher Education	34
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	PNPI	58
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Total 2020	48,6
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Companies	46,7
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	P.A.	60,2
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Higher Education	59,7
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	PNPI	66,7
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Total 2020	19
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Companies	19
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	P.A.	21,2
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Higher Education	13,4
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	PNPI	25
%Companies that have requested biotechnology patents in Biotechnology	Total 2020	22,9
%Companies that have requested biotechnology patents in Biotechnology	Companies	17,3
%Companies that have requested biotechnology patents in Biotechnology	P.A.	53,4
%Companies that have requested biotechnology patents in Biotechnology	Higher Education	73,1
%Companies that have requested biotechnology patents in Biotechnology	PNPI	8,3
Number of patents requested	Total 2020	1.991
Number of patents requested	Companies	681
Number of patents requested	P.A.	698
Number of patents requested	Higher Education	611
Number of patents requested	PNPI	1