Indicator type Main activity, secondary activity or tool required for... Total Companies carrying out R&D in Biotechnology Total 1,376 Companies carrying out R&D in Biotechnology Main 711 Companies carrying out R&D in Biotechnology Secondary 270 Companies carrying out R&D in Biotechnology Tool required 395 % Companies by type of biotechnology used: Genetic Code Total 31.4 % Companies by type of biotechnology used: Genetic Code Main 37.1 % Companies by type of biotechnology used: Genetic Code Secondary 28.5 % Companies by type of biotechnology used: Genetic Code Tool required 23.3 % Companies by type of biotechnology used: Functional Units Total 43.7 % Companies by type of biotechnology used: Functional Units Main 50.2 % Companies by type of biotechnology used: Functional Units Secondary 38.9 % Companies by type of biotechnology used: Functional Units Tool required 35.3 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Total 22.8 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Main 26.3 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Secondary 22.6 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Tool required 16.8 % Companies by type of biotechnology used: Bioprocesses Total 48.3 % Companies by type of biotechnology used: Bioprocesses Main 38.7 % Companies by type of biotechnology used: Bioprocesses Secondary 59.0 % Companies by type of biotechnology used: Bioprocesses Tool required 58.2 % Companies by type of biotechnology used: Subcellular Organisms Total 7.9 % Companies by type of biotechnology used: Subcellular Organisms Main 10.6 % Companies by type of biotechnology used: Subcellular Organisms Secondary 6.0 % Companies by type of biotechnology used: Subcellular Organisms Tool required 4.2 % Companies by type of biotechnology used: Bioinformatics Total 27.1 % Companies by type of biotechnology used: Bioinformatics Main 34.0 % Companies by type of biotechnology used: Bioinformatics Secondary 21.5 % Companies by type of biotechnology used: Bioinformatics Tool required 18.7 % Companies by type of biotechnology used: Nanobiotechnology Total 11.2 % Companies by type of biotechnology used: Nanobiotechnology Main 14.5 % Companies by type of biotechnology used: Nanobiotechnology Secondary 10.0 % Companies by type of biotechnology used: Nanobiotechnology Tool required 6.2 % Companies by type of biotechnology used: Other Total 17.6 % Companies by type of biotechnology used: Other Main 19.2 % Companies by type of biotechnology used: Other Secondary 17.3 % Companies by type of biotechnology used: Other Tool required 15.0 % Companies by final application areas of biotechnology use: Human Health Total 48.0 % Companies by final application areas of biotechnology use: Human Health Main 64.5 % Companies by final application areas of biotechnology use: Human Health Secondary 33.7 % Companies by final application areas of biotechnology use: Human Health Tool required 28.1 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Total 16.9 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Main 17.2 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Secondary 18.2 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Tool required 15.3 % Companies by final application areas of biotechnology use: Food Products Total 29.4 % Companies by final application areas of biotechnology use: Food Products Main 20.1 % Companies by final application areas of biotechnology use: Food Products Secondary 34.5 % Companies by final application areas of biotechnology use: Food Products Tool required 42.7 % Companies by final application areas of biotechnology use: Agriculture and Forestry Total 25.7 % Companies by final application areas of biotechnology use: Agriculture and Forestry Main 21.8 % Companies by final application areas of biotechnology use: Agriculture and Forestry Secondary 31.3 % Companies by final application areas of biotechnology use: Agriculture and Forestry Tool required 28.9 % Companies by final application areas of biotechnology use: Environment Total 18.0 % Companies by final application areas of biotechnology use: Environment Main 16.2 % Companies by final application areas of biotechnology use: Environment Secondary 24.6 % Companies by final application areas of biotechnology use: Environment Tool required 16.8 % Companies by final application areas of biotechnology use: Industry Total 13.0 % Companies by final application areas of biotechnology use: Industry Main 11.7 % Companies by final application areas of biotechnology use: Industry Secondary 17.2 % Companies by final application areas of biotechnology use: Industry Tool required 12.6 R&D personnel in Biotechnology (PP) Total 17,257 R&D personnel in Biotechnology (PP) Main 9,048 R&D personnel in Biotechnology (PP) Secondary 4,028 R&D personnel in Biotechnology (PP) Tool required 4,180 R&D personnel in Biotechnology (PP): Research personnel Total 9,195 R&D personnel in Biotechnology (PP): Research personnel Main 5,201 R&D personnel in Biotechnology (PP): Research personnel Secondary 2,189 R&D personnel in Biotechnology (PP): Research personnel Tool required 1,806 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Total 8,061 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Main 3,847 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Secondary 1,840 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Tool required 2,375 R&D personnel in Biotechnology (PP). Women Total 9,980 R&D personnel in Biotechnology (PP). Women Main 5,508 R&D personnel in Biotechnology (PP). Women Secondary 2,308 R&D personnel in Biotechnology (PP). Women Tool required 2,164 R&D personnel in Biotechnology (PP). Women: Research personnel Total 5,222 R&D personnel in Biotechnology (PP). Women: Research personnel Main 3,049 R&D personnel in Biotechnology (PP). Women: Research personnel Secondary 1,239 R&D personnel in Biotechnology (PP). Women: Research personnel Tool required 934 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Total 4,758 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Main 2,458 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Secondary 1,069 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Tool required 1,231 R&D personnel in Biotechnology (FTE) Total 12,883.4 R&D personnel in Biotechnology (FTE) Main 7,145.1 R&D personnel in Biotechnology (FTE) Secondary 2,868.7 R&D personnel in Biotechnology (FTE) Tool required 2,869.6 R&D personnel in Biotechnology (FTE): Research personnel Total 7,103.2 R&D personnel in Biotechnology (FTE): Research personnel Main 4,146.1 R&D personnel in Biotechnology (FTE): Research personnel Secondary 1,664.6 R&D personnel in Biotechnology (FTE): Research personnel Tool required 1,292.5 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Total 5,780.2 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Main 2,999.0 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Secondary 1,204.1 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Tool required 1,577.1 R&D personnel in Biotechnology (FTE). Women Total 7,600.6 R&D personnel in Biotechnology (FTE). Women Main 4,390.4 R&D personnel in Biotechnology (FTE). Women Secondary 1,697.6 R&D personnel in Biotechnology (FTE). Women Tool required 1,512.6 R&D personnel in Biotechnology (FTE). Women: Research personnel Total 4,057.0 R&D personnel in Biotechnology (FTE). Women: Research personnel Main 2,442.0 R&D personnel in Biotechnology (FTE). Women: Research personnel Secondary 931.4 R&D personnel in Biotechnology (FTE). Women: Research personnel Tool required 683.6 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Total 3,543.7 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Main 1,948.5 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Secondary 766.2 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Tool required 829.0 Expenditure on internal R&D in Biotechnology (thousands of euros) Total 1,283,346 Expenditure on internal R&D in Biotechnology (thousands of euros) Main 793,871 Expenditure on internal R&D in Biotechnology (thousands of euros) Secondary 225,886 Expenditure on internal R&D in Biotechnology (thousands of euros) Tool required 263,589 1) By type of expenditure: Current expenditure Total 1,180,187 1) By type of expenditure: Current expenditure Main 730,162 1) By type of expenditure: Current expenditure Secondary 206,423 1) By type of expenditure: Current expenditure Tool required 243,601 1.1) Labour expenditure of research personnel Total 372,421 1.1) Labour expenditure of research personnel Main 220,559 1.1) Labour expenditure of research personnel Secondary 79,909 1.1) Labour expenditure of research personnel Tool required 71,953 1.2) Labour expenditure of technical and auxiliary personnel Total 229,734 1.2) Labour expenditure of technical and auxiliary personnel Main 122,582 1.2) Labour expenditure of technical and auxiliary personnel Secondary 46,028 1.2) Labour expenditure of technical and auxiliary personnel Tool required 61,124 1.3) Other current expenditure Total 578,032 1.3) Other current expenditure Main 387,021 1.3) Other current expenditure Secondary 80,486 1.3) Other current expenditure Tool required 110,525 2) By type of expenditure: Capital expenditure Total 103,159 2) By type of expenditure: Capital expenditure Main 63,708 2) By type of expenditure: Capital expenditure Secondary 19,463 2) By type of expenditure: Capital expenditure Tool required 19,988 2.1) Land and buildings Total 10,889 2.1) Land and buildings Main 6,242 2.1) Land and buildings Secondary 1,295 2.1) Land and buildings Tool required 3,353 2.2) Equipment and tools Total 59,204 2.2) Equipment and tools Main 32,289 2.2) Equipment and tools Secondary 13,987 2.2) Equipment and tools Tool required 12,928 2.3) Acquisition of specific R&D software Total 5,623 2.3) Acquisition of specific R&D software Main 4,542 2.3) Acquisition of specific R&D software Secondary 423 2.3) Acquisition of specific R&D software Tool required 659 2.4) Other R&D-specific IP products Total 27,442 2.4) Other R&D-specific IP products Main 20,636 2.4) Other R&D-specific IP products Secondary 3,758 2.4) Other R&D-specific IP products Tool required 3,049 1.1) By origin of funds: Own funds Total 887,527 1.1) By origin of funds: Own funds Main 533,621 1.1) By origin of funds: Own funds Secondary 160,796 1.1) By origin of funds: Own funds Tool required 193,110 1.2) By origin of funds: Funds from the Business sector Total 143,903 1.2) By origin of funds: Funds from the Business sector Main 105,847 1.2) By origin of funds: Funds from the Business sector Secondary 15,390 1.2) By origin of funds: Funds from the Business sector Tool required 22,666 1.3) By origin of funds: Funds from the Public Administration sector Total 126,546 1.3) By origin of funds: Funds from the Public Administration sector Main 77,642 1.3) By origin of funds: Funds from the Public Administration sector Secondary 25,443 1.3) By origin of funds: Funds from the Public Administration sector Tool required 23,461 1.4) By origin of funds: Funds from the Higher Education sector Total 94 1.4) By origin of funds: Funds from the Higher Education sector Main 76 1.4) By origin of funds: Funds from the Higher Education sector Secondary 0 1.4) By origin of funds: Funds from the Higher Education sector Tool required 18 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Total 12,623 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Main 11,461 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Secondary 99 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Tool required 1,063 1.6) By origin of funds: Funds from the rest of the world Total 112,652 1.6) By origin of funds: Funds from the rest of the world Main 65,223 1.6) By origin of funds: Funds from the rest of the world Secondary 24,158 1.6) By origin of funds: Funds from the rest of the world Tool required 23,271 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Total 137,432 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Main 118,571 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Secondary 11,344 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Tool required 7,517 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Total 88,127 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Main 73,357 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Secondary 8,570 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Tool required 6,200 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Total 49,305 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Main 45,214 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Secondary 2,774 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Tool required 1,318 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Total 43.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Main 52.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Secondary 38.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Tool required 32.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Total 16.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Main 15.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Secondary 21.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Tool required 14.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Total 23.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Main 25.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Secondary 21.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Tool required 22.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Total 14.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Main 14.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Secondary 15.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Tool required 13.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Total 18.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Main 20.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Secondary 17.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Tool required 14.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Total 19.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Main 22.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Secondary 17.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Tool required 15.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Total 19.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Main 18.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Secondary 21.8 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Tool required 18.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Total 49.8 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Main 54.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Secondary 46.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Tool required 43.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Total 59.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Main 66.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Secondary 57.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Tool required 48.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Total 22.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Main 22.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Secondary 20.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Tool required 23.7 % Companies with international revenues related to biotechnology activities Total 23.6 % Companies with international revenues related to biotechnology activities Main 30.8 % Companies with international revenues related to biotechnology activities Secondary 19.3 % Companies with international revenues related to biotechnology activities Tool required 13.3 % Companies representing international revenues related to biotechnology activities Total 1.5 % Companies representing international revenues related to biotechnology activities Main 14.7 % Companies representing international revenues related to biotechnology activities Secondary 0.4 % Companies representing international revenues related to biotechnology activities Tool required 0.8 % International revenues related to biotechnology activities distributed in: Revenues from the EU Total 57.6 % International revenues related to biotechnology activities distributed in: Revenues from the EU Main 64.5 % International revenues related to biotechnology activities distributed in: Revenues from the EU Secondary 38.7 % International revenues related to biotechnology activities distributed in: Revenues from the EU Tool required 47.7 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Total 42.4 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Main 35.5 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Secondary 61.3 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Tool required 52.3 % International revenues related to biotechnology activities by classification: International trade in goods and services Total 82.3 % International revenues related to biotechnology activities by classification: International trade in goods and services Main 77.1 % International revenues related to biotechnology activities by classification: International trade in goods and services Secondary 90.6 % International revenues related to biotechnology activities by classification: International trade in goods and services Tool required 95.7 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Total 14.1 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Main 20.2 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Secondary 0.5 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Tool required 2.3 % International revenues related to biotechnology activities by classification: Subsidies from external sources Total 1.5 % International revenues related to biotechnology activities by classification: Subsidies from external sources Main 1.1 % International revenues related to biotechnology activities by classification: Subsidies from external sources Secondary 3.7 % International revenues related to biotechnology activities by classification: Subsidies from external sources Tool required 1.0 % International revenues related to biotechnology activities by classification: Other Total 2.1 % International revenues related to biotechnology activities by classification: Other Main 1.6 % International revenues related to biotechnology activities by classification: Other Secondary 5.1 % International revenues related to biotechnology activities by classification: Other Tool required 1.0