Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;1.006 No. of companies carrying out R&D in Biotechnology;250 or more employees;73 No. of companies carrying out R&D in Biotechnology;Total;1.079 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;34 %Companies according to biotechnology used: Genetic code;250 or more employees;55 %Companies according to biotechnology used: Genetic code;Total;35 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;44 %Companies according to biotechnology used: Functional units;250 or more employees;53 %Companies according to biotechnology used: Functional units;Total;44 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;25 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;47 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;26 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;48 %Companies according to biotechnology used: Bioprocesses;250 or more employees;64 %Companies according to biotechnology used: Bioprocesses;Total;49 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;8 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;15 %Companies according to biotechnology used: Sub-cellular organisms;Total;8 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;23 %Companies according to biotechnology used: Bio-computing;250 or more employees;23 %Companies according to biotechnology used: Bio-computing;Total;23 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;15 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;12 %Companies according to biotechnology used: Nanobiotechnology;Total;15 %Companies according to biotechnology used: Other;Fewer than 250 employees;12 %Companies according to biotechnology used: Other;250 or more employees;11 %Companies according to biotechnology used: Other;Total;12 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;503 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;16 Companies in which biotechnology activities are: Main and/or exclusive;Total;519 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;158 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;21 Companies in which biotechnology activities are: A secondary line of business;Total;179 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;345 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;36 Companies in which biotechnology activities are: A tool necessary for production;Total;381 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;47 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;51 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;48 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;22 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;4 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;21 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;33 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;34 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;33 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;22 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;21 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;22 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;17 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;21 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;17 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;15 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;8 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;15 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;7.556 Personnel in R&D in biotechnology (no. of persons);250 or more employees;2.239 Personnel in R&D in biotechnology (no. of persons);Total;9.795 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4.379 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1.194 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;5.573 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3.177 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1.045 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;4.222 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4.032 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;1.267 Personnel in R&D in biotechnology (no. of persons): women;Total;5.298 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2.279 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;646 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;2.925 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1.752 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;621 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;2.373 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5.209,9 Personnel in R&D in biotechnology (FTE);250 or more employees;1.618,7 Personnel in R&D in biotechnology (FTE);Total;6.828,6 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3.191,6 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;914,9 Personnel in R&D in biotechnology (FTE): Researchers;Total;4.106,5 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2.018,3 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;703,8 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;2.722,1 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;2.872,2 Personnel in R&D in biotechnology (FTE): women;250 or more employees;939,6 Personnel in R&D in biotechnology (FTE): women;Total;3.811,7 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1.682,6 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;508,1 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2.190,7 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1.189,5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;431,5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;1.621 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;402.391 Internal expenditure on R&D (thousands of euros);250 or more employees;131.434 Internal expenditure on R&D (thousands of euros);Total;533.826 1) By nature of the expense: Current expenses;Fewer than 250 employees;365.997 1) By nature of the expense: Current expenses;250 or more employees;126.959 1) By nature of the expense: Current expenses;Total;492.955 1.1) Remuneration to researchers;Fewer than 250 employees;153.274 1.1) Remuneration to researchers;250 or more employees;50.166 1.1) Remuneration to researchers;Total;203.439 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;67.291 1.2) Remuneration to technicians and assistants;250 or more employees;29.559 1.2) Remuneration to technicians and assistants;Total;96.850 1.3) Other current expenses;Fewer than 250 employees;145.432 1.3) Other current expenses;250 or more employees;47.234 1.3) Other current expenses;Total;192.666 2) By nature of the expense: Capital expenses;Fewer than 250 employees;36.395 2) By nature of the expense: Capital expenses;250 or more employees;4.476 2) By nature of the expense: Capital expenses;Total;40.870 2.1) Land and buildings;Fewer than 250 employees;6.634 2.1) Land and buildings;250 or more employees;888 2.1) Land and buildings;Total;7.521 2.2) Equipment and instruments;Fewer than 250 employees;28.690 2.2) Equipment and instruments;250 or more employees;3.388 2.2) Equipment and instruments;Total;32.078 2.3) Acquisition of specific R&D software;Fewer than 250 employees;1.071 2.3) Acquisition of specific R&D software;250 or more employees;200 2.3) Acquisition of specific R&D software;Total;1.270 1) By origin of the funds: National funds;Fewer than 250 employees;329.975 1) By origin of the funds: National funds;250 or more employees;102.895 1) By origin of the funds: National funds;Total;432.869 1.1) Own funds;Fewer than 250 employees;239.006 1.1) Own funds;250 or more employees;80.039 1.1) Own funds;Total;319.046 1.2) From companies;Fewer than 250 employees;30.715 1.2) From companies;250 or more employees;8.538 1.2) From companies;Total;39.253 1.3) Public Administration funds;Fewer than 250 employees;57.667 1.3) Public Administration funds;250 or more employees;12.396 1.3) Public Administration funds;Total;70.063 1.4) From Universities;Fewer than 250 employees;156 1.4) From Universities;250 or more employees;0 1.4) From Universities;Total;156 1.5) From non profit private institutions;Fewer than 250 employees;2.431 1.5) From non profit private institutions;250 or more employees;1.921 1.5) From non profit private institutions;Total;4.351 1) By origin of the funds: Foreign funds;Fewer than 250 employees;72.416 1) By origin of the funds: Foreign funds;250 or more employees;28.540 1) By origin of the funds: Foreign funds;Total;100.956 2.1) From EU programmes;Fewer than 250 employees;18.073 2.1) From EU programmes;250 or more employees;1.998 2.1) From EU programmes;Total;20.070 2.2) Other foreign funds;Fewer than 250 employees;54.344 2.2) Other foreign funds;250 or more employees;26.542 2.2) Other foreign funds;Total;80.886 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;76.625 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;62.000 Purchase of R&D services in biotechnology (thousands of euros);Total;138.625 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;64.575 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;36.539 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;101.114 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;12.050 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;25.462 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;37.512 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;48 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;25 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;46 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;12 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;19 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;19 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;20 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;19 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;21 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;37 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;36 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;37 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;50 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;44 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;49 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;20 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;11 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;19 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;22 % Companies that have requested biotechnology patents in Biotechnology;Total;15 Number of patents requested;Fewer than 250 employees;397 Number of patents requested;250 or more employees;69 Number of patents requested;Total;466 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;25,3 % Companies with income of an international origin related to biotechnological activities;250 or more employees;20,5 % Companies with income of an international origin related to biotechnological activities;Total;24,9 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;4 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;0,7 % Turnover representing income of an international origin related to biotechnological activities;Total;0,9 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;49,5 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;81 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;71,3 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;50,5 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;19,1 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;28,7 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;76,2 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;99,2 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;92,2 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;7,8 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;. % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;2,4 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;3,2 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;0,4 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;1,3 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;12,7 % Income of an international origin related with activities according to the classification: Other;250 or more employees;0,4 % Income of an international origin related with activities according to the classification: Other;Total;4,2