Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;1.010 No. of companies carrying out R&D in Biotechnology;250 or more employees;69 No. of companies carrying out R&D in Biotechnology;Total;1.078 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;34 %Companies according to biotechnology used: Genetic code;250 or more employees;49 %Companies according to biotechnology used: Genetic code;Total;35 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;41 %Companies according to biotechnology used: Functional units;250 or more employees;54 %Companies according to biotechnology used: Functional units;Total;42 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;25 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;48 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;27 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;48 %Companies according to biotechnology used: Bioprocesses;250 or more employees;59 %Companies according to biotechnology used: Bioprocesses;Total;49 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;7 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;12 %Companies according to biotechnology used: Sub-cellular organisms;Total;8 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;22 %Companies according to biotechnology used: Bio-computing;250 or more employees;22 %Companies according to biotechnology used: Bio-computing;Total;22 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;14 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;18 %Companies according to biotechnology used: Nanobiotechnology;Total;14 %Companies according to biotechnology used: Other;Fewer than 250 employees;12 %Companies according to biotechnology used: Other;250 or more employees;8 %Companies according to biotechnology used: Other;Total;12 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;511 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;15 Companies in which biotechnology activities are: Main and/or exclusive;Total;526 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;155 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;18 Companies in which biotechnology activities are: A secondary line of business;Total;173 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;344 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;35 Companies in which biotechnology activities are: A tool necessary for production;Total;379 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;48 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;50 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;48 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;21 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;5 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;20 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;32 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;36 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;33 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;24 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;21 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;24 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;15 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;15 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;15 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;14 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;6 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;14 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;7.849 Personnel in R&D in biotechnology (no. of persons);250 or more employees;2.342 Personnel in R&D in biotechnology (no. of persons);Total;10.191 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4.469 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1.305 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;5.774 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3.380 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1.037 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;4.417 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4.199 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;1.326 Personnel in R&D in biotechnology (no. of persons): women;Total;5.525 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2.320 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;695 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;3.015 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1.879 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;631 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;2.511 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5.530,1 Personnel in R&D in biotechnology (FTE);250 or more employees;1.661,2 Personnel in R&D in biotechnology (FTE);Total;7.191,4 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3.333 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;943,6 Personnel in R&D in biotechnology (FTE): Researchers;Total;4.276,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2.197,1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;717,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;2.914,7 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;3.061 Personnel in R&D in biotechnology (FTE): women;250 or more employees;924,4 Personnel in R&D in biotechnology (FTE): women;Total;3.985,4 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1.742,1 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;491,9 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2.234 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1.318,9 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;432,5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;1.751,4 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;441.736 Internal expenditure on R&D (thousands of euros);250 or more employees;136.435 Internal expenditure on R&D (thousands of euros);Total;578.171 1) By nature of the expense: Current expenses;Fewer than 250 employees;387.035 1) By nature of the expense: Current expenses;250 or more employees;130.565 1) By nature of the expense: Current expenses;Total;517.601 1.1) Remuneration to researchers;Fewer than 250 employees;158.420 1.1) Remuneration to researchers;250 or more employees;55.335 1.1) Remuneration to researchers;Total;213.755 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;74.027 1.2) Remuneration to technicians and assistants;250 or more employees;24.413 1.2) Remuneration to technicians and assistants;Total;98.440 1.3) Other current expenses;Fewer than 250 employees;154.588 1.3) Other current expenses;250 or more employees;50.818 1.3) Other current expenses;Total;205.406 2) By nature of the expense: Capital expenses;Fewer than 250 employees;54.701 2) By nature of the expense: Capital expenses;250 or more employees;5.870 2) By nature of the expense: Capital expenses;Total;60.570 2.1) Land and buildings;Fewer than 250 employees;22.554 2.1) Land and buildings;250 or more employees;54 2.1) Land and buildings;Total;22.609 2.2) Equipment and instruments;Fewer than 250 employees;30.685 2.2) Equipment and instruments;250 or more employees;5.483 2.2) Equipment and instruments;Total;36.169 2.3) Acquisition of specific R&D software;Fewer than 250 employees;1.461 2.3) Acquisition of specific R&D software;250 or more employees;332 2.3) Acquisition of specific R&D software;Total;1.793 1) By origin of the funds: National funds;Fewer than 250 employees;379.550 1) By origin of the funds: National funds;250 or more employees;108.064 1) By origin of the funds: National funds;Total;487.615 1.1) Own funds;Fewer than 250 employees;249.390 1.1) Own funds;250 or more employees;81.068 1.1) Own funds;Total;330.459 1.2) From companies;Fewer than 250 employees;32.831 1.2) From companies;250 or more employees;12.630 1.2) From companies;Total;45.462 1.3) Public Administration funds;Fewer than 250 employees;53.162 1.3) Public Administration funds;250 or more employees;13.028 1.3) Public Administration funds;Total;66.189 1.4) From Universities;Fewer than 250 employees;25.148 1.4) From Universities;250 or more employees;. 1.4) From Universities;Total;25.148 1.5) From non profit private institutions;Fewer than 250 employees;19.019 1.5) From non profit private institutions;250 or more employees;1.338 1.5) From non profit private institutions;Total;20.357 1) By origin of the funds: Foreign funds;Fewer than 250 employees;62.186 1) By origin of the funds: Foreign funds;250 or more employees;28.371 1) By origin of the funds: Foreign funds;Total;90.556 2.1) From EU programmes;Fewer than 250 employees;18.782 2.1) From EU programmes;250 or more employees;2.150 2.1) From EU programmes;Total;20.932 2.2) Other foreign funds;Fewer than 250 employees;43.403 2.2) Other foreign funds;250 or more employees;26.221 2.2) Other foreign funds;Total;69.624 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;111.514 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;54.508 Purchase of R&D services in biotechnology (thousands of euros);Total;166.022 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;67.448 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;30.007 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;97.455 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;44.065 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;24.501 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;68.567 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;47 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;30 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;46 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;35 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;36 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;35 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;50 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;34 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;49 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;22 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;9 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;21 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;21 % Companies that have requested biotechnology patents in Biotechnology;Total;15 Number of patents requested;Fewer than 250 employees;451 Number of patents requested;250 or more employees;75 Number of patents requested;Total;526 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;26,4 % Companies with income of an international origin related to biotechnological activities;250 or more employees;19,1 % Companies with income of an international origin related to biotechnological activities;Total;26 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;6,5 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;0,8 % Turnover representing income of an international origin related to biotechnological activities;Total;1,4 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;51,6 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;76,3 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;63,8 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;48,4 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;23,7 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;36,2 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;85,6 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;97,7 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;91,6 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;1,4 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;0,5 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;0,9 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;3 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;0,7 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;1,9 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;10,1 % Income of an international origin related with activities according to the classification: Other;250 or more employees;1,1 % Income of an international origin related with activities according to the classification: Other;Total;5,6