Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;1.061 No. of companies carrying out R&D in Biotechnology;250 or more employees;73 No. of companies carrying out R&D in Biotechnology;Total;1.133 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;30 %Companies according to biotechnology used: Genetic code;250 or more employees;50 %Companies according to biotechnology used: Genetic code;Total;32 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;40 %Companies according to biotechnology used: Functional units;250 or more employees;51 %Companies according to biotechnology used: Functional units;Total;41 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;26 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;46 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;27 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;47 %Companies according to biotechnology used: Bioprocesses;250 or more employees;64 %Companies according to biotechnology used: Bioprocesses;Total;48 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;8 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;20 %Companies according to biotechnology used: Sub-cellular organisms;Total;8 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;21 %Companies according to biotechnology used: Bio-computing;250 or more employees;31 %Companies according to biotechnology used: Bio-computing;Total;21 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;14 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;18 %Companies according to biotechnology used: Nanobiotechnology;Total;14 %Companies according to biotechnology used: Other;Fewer than 250 employees;13 %Companies according to biotechnology used: Other;250 or more employees;10 %Companies according to biotechnology used: Other;Total;13 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;549 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;15 Companies in which biotechnology activities are: Main and/or exclusive;Total;564 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;193 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;19 Companies in which biotechnology activities are: A secondary line of business;Total;212 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;319 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;38 Companies in which biotechnology activities are: A tool necessary for production;Total;358 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;50 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;51 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;50 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;20 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;1 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;19 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;29 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;36 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;29 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;22 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;18 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;21 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;11 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;13 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;14 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;7 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;13 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;7.883 Personnel in R&D in biotechnology (no. of persons);250 or more employees;2.823 Personnel in R&D in biotechnology (no. of persons);Total;10.706 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4.706 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1.521 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;6.227 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3.177 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1.302 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;4.479 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4.068 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;1.727 Personnel in R&D in biotechnology (no. of persons): women;Total;5.795 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2.417 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;852 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;3.269 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1.652 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;875 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;2.527 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5.599 Personnel in R&D in biotechnology (FTE);250 or more employees;2.117,4 Personnel in R&D in biotechnology (FTE);Total;7.716,4 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3.511,8 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;1.091,3 Personnel in R&D in biotechnology (FTE): Researchers;Total;4.603,1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2.087,2 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;1.026,1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;3.113,3 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;2.969,5 Personnel in R&D in biotechnology (FTE): women;250 or more employees;1.323,4 Personnel in R&D in biotechnology (FTE): women;Total;4.292,9 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1.832,2 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;614,2 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2.446,4 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1.137,3 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;709,2 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;1.846,5 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;452.121 Internal expenditure on R&D (thousands of euros);250 or more employees;163.932 Internal expenditure on R&D (thousands of euros);Total;616.053 1) By nature of the expense: Current expenses;Fewer than 250 employees;413.906 1) By nature of the expense: Current expenses;250 or more employees;160.340 1) By nature of the expense: Current expenses;Total;574.245 1.1) Remuneration to researchers;Fewer than 250 employees;160.779 1.1) Remuneration to researchers;250 or more employees;60.962 1.1) Remuneration to researchers;Total;221.741 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;61.960 1.2) Remuneration to technicians and assistants;250 or more employees;40.504 1.2) Remuneration to technicians and assistants;Total;102.464 1.3) Other current expenses;Fewer than 250 employees;191.167 1.3) Other current expenses;250 or more employees;58.874 1.3) Other current expenses;Total;250.041 2) By nature of the expense: Capital expenses;Fewer than 250 employees;38.215 2) By nature of the expense: Capital expenses;250 or more employees;3.593 2) By nature of the expense: Capital expenses;Total;41.808 2.1) Land and buildings;Fewer than 250 employees;4.988 2.1) Land and buildings;250 or more employees;371 2.1) Land and buildings;Total;5.359 2.2) Equipment and instruments;Fewer than 250 employees;26.997 2.2) Equipment and instruments;250 or more employees;2.493 2.2) Equipment and instruments;Total;29.489 2.3) Acquisition of specific R&D software;Fewer than 250 employees;1.716 2.3) Acquisition of specific R&D software;250 or more employees;590 2.3) Acquisition of specific R&D software;Total;2.306 2.4) Otros productos de propiedad intelectual específicos para I+D;Fewer than 250 employees;4.515 2.4) Otros productos de propiedad intelectual específicos para I+D;250 or more employees;139 2.4) Otros productos de propiedad intelectual específicos para I+D;Total;4.654 1) By origin of the funds: National funds;Fewer than 250 employees;388.127 1) By origin of the funds: National funds;250 or more employees;123.833 1) By origin of the funds: National funds;Total;511.960 1.1) Own funds;Fewer than 250 employees;294.928 1.1) Own funds;250 or more employees;87.407 1.1) Own funds;Total;382.335 1.2) From companies;Fewer than 250 employees;29.072 1.2) From companies;250 or more employees;15.952 1.2) From companies;Total;45.024 1.3) Public Administration funds;Fewer than 250 employees;60.976 1.3) Public Administration funds;250 or more employees;11.410 1.3) Public Administration funds;Total;72.387 1.4) From Universities;Fewer than 250 employees;363 1.4) From Universities;250 or more employees;0 1.4) From Universities;Total;363 1.5) From non profit private institutions;Fewer than 250 employees;2.788 1.5) From non profit private institutions;250 or more employees;9.064 1.5) From non profit private institutions;Total;11.851 1) By origin of the funds: Foreign funds;Fewer than 250 employees;63.994 1) By origin of the funds: Foreign funds;250 or more employees;40.100 1) By origin of the funds: Foreign funds;Total;104.093 2.1) From EU programmes;Fewer than 250 employees;18.363 2.1) From EU programmes;250 or more employees;3.462 2.1) From EU programmes;Total;21.825 2.2) Other foreign funds;Fewer than 250 employees;45.631 2.2) Other foreign funds;250 or more employees;36.638 2.2) Other foreign funds;Total;82.269 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;88.908 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;55.434 Purchase of R&D services in biotechnology (thousands of euros);Total;144.342 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;35.758 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;34.700 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;70.458 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;53.150 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;20.734 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;73.885 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;49 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;29 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;48 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;15 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;12 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;36 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;35 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;36 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;49 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;39 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;49 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;18 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;16 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;12 % Companies that have requested biotechnology patents in Biotechnology;Total;16 Number of patents requested;Fewer than 250 employees;570 Number of patents requested;250 or more employees;63 Number of patents requested;Total;633 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;24,2 % Companies with income of an international origin related to biotechnological activities;250 or more employees;20,7 % Companies with income of an international origin related to biotechnological activities;Total;24 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;6,1 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;0,9 % Turnover representing income of an international origin related to biotechnological activities;Total;1,4 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;37,3 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;75,7 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;57,3 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;62,7 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;24,3 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;42,7 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;96,3 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;69,4 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;82,3 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;2,4 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;29,4 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;16,5 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;1,1 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;0,9 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;1 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;0,2 % Income of an international origin related with activities according to the classification: Other;250 or more employees;0,3 % Income of an international origin related with activities according to the classification: Other;Total;0,3