Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;975 No. of companies carrying out R&D in Biotechnology;250 or more employees;81 No. of companies carrying out R&D in Biotechnology;Total;1,056 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;35 %Companies according to biotechnology used: Genetic code;250 or more employees;46 %Companies according to biotechnology used: Genetic code;Total;36 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;44 %Companies according to biotechnology used: Functional units;250 or more employees;50 %Companies according to biotechnology used: Functional units;Total;45 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;26 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;45 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;27 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;45 %Companies according to biotechnology used: Bioprocesses;250 or more employees;66 %Companies according to biotechnology used: Bioprocesses;Total;47 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;8 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;15 %Companies according to biotechnology used: Sub-cellular organisms;Total;8 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;24 %Companies according to biotechnology used: Bio-computing;250 or more employees;32 %Companies according to biotechnology used: Bio-computing;Total;25 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;13 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;16 %Companies according to biotechnology used: Nanobiotechnology;Total;13 %Companies according to biotechnology used: Other;Fewer than 250 employees;15 %Companies according to biotechnology used: Other;250 or more employees;13 %Companies according to biotechnology used: Other;Total;15 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;538 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;12 Companies in which biotechnology activities are: Main and/or exclusive;Total;551 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;164 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;19 Companies in which biotechnology activities are: A secondary line of business;Total;183 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;273 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;50 Companies in which biotechnology activities are: A tool necessary for production;Total;323 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;49 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;52 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;49 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;22 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;3 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;20 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;30 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;36 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;30 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;23 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;13 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;23 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;17 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;13 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;7 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;12 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;7,908 Personnel in R&D in biotechnology (no. of persons);250 or more employees;2,811 Personnel in R&D in biotechnology (no. of persons);Total;10,719 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4,660 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1,470 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;6,131 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3,247 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1,341 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;4,588 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4,291 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;1,749 Personnel in R&D in biotechnology (no. of persons): women;Total;6,040 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2,520 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;891 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;3,411 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1,772 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;857 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;2,629 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5,651.3 Personnel in R&D in biotechnology (FTE);250 or more employees;2,099.5 Personnel in R&D in biotechnology (FTE);Total;7,750.8 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3,461.8 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;1,056.3 Personnel in R&D in biotechnology (FTE): Researchers;Total;4,518.1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2,189.4 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;1,043.3 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;3,232.7 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;3,133.9 Personnel in R&D in biotechnology (FTE): women;250 or more employees;1,337.5 Personnel in R&D in biotechnology (FTE): women;Total;4,471.4 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1,912.0 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;650.7 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2,562.7 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1,221.9 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;686.8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;1,908.7 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;511,004 Internal expenditure on R&D (thousands of euros);250 or more employees;168,555 Internal expenditure on R&D (thousands of euros);Total;679,558 1) By nature of the expense: Current expenses;Fewer than 250 employees;470,651 1) By nature of the expense: Current expenses;250 or more employees;163,981 1) By nature of the expense: Current expenses;Total;634,631 1.1) Remuneration to researchers;Fewer than 250 employees;167,208 1.1) Remuneration to researchers;250 or more employees;61,649 1.1) Remuneration to researchers;Total;228,857 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;63,658 1.2) Remuneration to technicians and assistants;250 or more employees;40,840 1.2) Remuneration to technicians and assistants;Total;104,498 1.3) Other current expenses;Fewer than 250 employees;239,785 1.3) Other current expenses;250 or more employees;61,492 1.3) Other current expenses;Total;301,276 2) By nature of the expense: Capital expenses;Fewer than 250 employees;40,353 2) By nature of the expense: Capital expenses;250 or more employees;4,574 2) By nature of the expense: Capital expenses;Total;44,927 2.1) Land and buildings;Fewer than 250 employees;2,519 2.1) Land and buildings;250 or more employees;66 2.1) Land and buildings;Total;2,585 2.2) Equipment and instruments;Fewer than 250 employees;19,828 2.2) Equipment and instruments;250 or more employees;3,741 2.2) Equipment and instruments;Total;23,569 2.3) Acquisition of specific R&D software;Fewer than 250 employees;780 2.3) Acquisition of specific R&D software;250 or more employees;612 2.3) Acquisition of specific R&D software;Total;1,392 2.4) Otros productos de propiedad intelectual específicos para I+D;Fewer than 250 employees;17,226 2.4) Otros productos de propiedad intelectual específicos para I+D;250 or more employees;155 2.4) Otros productos de propiedad intelectual específicos para I+D;Total;17,381 1) By origin of the funds: National funds;Fewer than 250 employees;417,983 1) By origin of the funds: National funds;250 or more employees;138,313 1) By origin of the funds: National funds;Total;556,297 1.1) Own funds;Fewer than 250 employees;301,946 1.1) Own funds;250 or more employees;85,064 1.1) Own funds;Total;387,010 1.2) From companies;Fewer than 250 employees;49,801 1.2) From companies;250 or more employees;36,223 1.2) From companies;Total;86,025 1.3) Public Administration funds;Fewer than 250 employees;61,218 1.3) Public Administration funds;250 or more employees;13,546 1.3) Public Administration funds;Total;74,764 1.4) From Universities;Fewer than 250 employees;408 1.4) From Universities;250 or more employees;0 1.4) From Universities;Total;408 1.5) From non profit private institutions;Fewer than 250 employees;4,610 1.5) From non profit private institutions;250 or more employees;3,480 1.5) From non profit private institutions;Total;8,090 1) By origin of the funds: Foreign funds;Fewer than 250 employees;93,020 1) By origin of the funds: Foreign funds;250 or more employees;30,241 1) By origin of the funds: Foreign funds;Total;123,262 2.1) From EU programmes;Fewer than 250 employees;18,993 2.1) From EU programmes;250 or more employees;6,132 2.1) From EU programmes;Total;25,125 2.2) Other foreign funds;Fewer than 250 employees;74,027 2.2) Other foreign funds;250 or more employees;24,109 2.2) Other foreign funds;Total;98,137 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;86,267 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;61,292 Purchase of R&D services in biotechnology (thousands of euros);Total;147,558 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;26,503 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;50,373 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;76,875 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;59,764 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;10,919 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;70,683 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;50 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;25 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;49 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;11 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;13 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;19 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;8 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;38 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;30 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;37 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;52 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;40 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;51 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;18 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;18 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;16 % Companies that have requested biotechnology patents in Biotechnology;Total;16 Number of patents requested;Fewer than 250 employees;602 Number of patents requested;250 or more employees;144 Number of patents requested;Total;746 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;23.9 % Companies with income of an international origin related to biotechnological activities;250 or more employees;16.0 % Companies with income of an international origin related to biotechnological activities;Total;23.3 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;5.70 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;0.70 % Turnover representing income of an international origin related to biotechnological activities;Total;1.20 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;49.30 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;69.70 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;60.40 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;50.70 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;30.30 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;39.60 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;92.60 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;71.20 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;80.90 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;5.50 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;27.90 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;17.80 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;1.90 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;0.80 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;1.30 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;0.10 % Income of an international origin related with activities according to the classification: Other;250 or more employees;. % Income of an international origin related with activities according to the classification: Other;Total;0.10