Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;1,040 No. of companies carrying out R&D in Biotechnology;250 or more employees;93 No. of companies carrying out R&D in Biotechnology;Total;1,133 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;32 %Companies according to biotechnology used: Genetic code;250 or more employees;43 %Companies according to biotechnology used: Genetic code;Total;33 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;40 %Companies according to biotechnology used: Functional units;250 or more employees;51 %Companies according to biotechnology used: Functional units;Total;41 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;22 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;41 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;24 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;48 %Companies according to biotechnology used: Bioprocesses;250 or more employees;69 %Companies according to biotechnology used: Bioprocesses;Total;50 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;5 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;12 %Companies according to biotechnology used: Sub-cellular organisms;Total;6 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;24 %Companies according to biotechnology used: Bio-computing;250 or more employees;28 %Companies according to biotechnology used: Bio-computing;Total;24 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;13 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;13 %Companies according to biotechnology used: Nanobiotechnology;Total;13 %Companies according to biotechnology used: Other;Fewer than 250 employees;15 %Companies according to biotechnology used: Other;250 or more employees;8 %Companies according to biotechnology used: Other;Total;14 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;581 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;22 Companies in which biotechnology activities are: Main and/or exclusive;Total;603 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;155 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;18 Companies in which biotechnology activities are: A secondary line of business;Total;173 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;305 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;53 Companies in which biotechnology activities are: A tool necessary for production;Total;357 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;45 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;49 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;45 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;19 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;3 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;18 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;30 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;39 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;31 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;23 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;17 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;22 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;17 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;14 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;9 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;12 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;8,124 Personnel in R&D in biotechnology (no. of persons);250 or more employees;3,386 Personnel in R&D in biotechnology (no. of persons);Total;11,510 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4,552 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1,650 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;6,202 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3,572 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1,736 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;5,308 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4,363 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;2,026 Personnel in R&D in biotechnology (no. of persons): women;Total;6,389 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2,368 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;935 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;3,304 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1,995 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;1,090 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;3,086 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5,788.1 Personnel in R&D in biotechnology (FTE);250 or more employees;2,448.9 Personnel in R&D in biotechnology (FTE);Total;8,236.9 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3,364.3 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;1,231.9 Personnel in R&D in biotechnology (FTE): Researchers;Total;4,596.1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2,423.8 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;1,217.0 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;3,640.8 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;3,197.5 Personnel in R&D in biotechnology (FTE): women;250 or more employees;1,501.0 Personnel in R&D in biotechnology (FTE): women;Total;4,698.5 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1,803.7 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;708.8 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2,512.5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1,393.8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;792.2 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;2,186.0 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;558,184 Internal expenditure on R&D (thousands of euros);250 or more employees;211,247 Internal expenditure on R&D (thousands of euros);Total;769,431 1) By nature of the expense: Current expenses;Fewer than 250 employees;518,032 1) By nature of the expense: Current expenses;250 or more employees;201,684 1) By nature of the expense: Current expenses;Total;719,715 1.1) Remuneration to researchers;Fewer than 250 employees;154,555 1.1) Remuneration to researchers;250 or more employees;66,892 1.1) Remuneration to researchers;Total;221,447 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;72,617 1.2) Remuneration to technicians and assistants;250 or more employees;50,192 1.2) Remuneration to technicians and assistants;Total;122,809 1.3) Other current expenses;Fewer than 250 employees;290,860 1.3) Other current expenses;250 or more employees;84,599 1.3) Other current expenses;Total;375,459 2) By nature of the expense: Capital expenses;Fewer than 250 employees;40,152 2) By nature of the expense: Capital expenses;250 or more employees;9,563 2) By nature of the expense: Capital expenses;Total;49,715 2.1) Land and buildings;Fewer than 250 employees;6,661 2.1) Land and buildings;250 or more employees;2,860 2.1) Land and buildings;Total;9,521 2.2) Equipment and instruments;Fewer than 250 employees;24,465 2.2) Equipment and instruments;250 or more employees;6,001 2.2) Equipment and instruments;Total;30,466 2.3) Acquisition of specific R&D software;Fewer than 250 employees;1,157 2.3) Acquisition of specific R&D software;250 or more employees;653 2.3) Acquisition of specific R&D software;Total;1,810 2.4) Otros productos de propiedad intelectual específicos para I+D;Fewer than 250 employees;7,869 2.4) Otros productos de propiedad intelectual específicos para I+D;250 or more employees;49 2.4) Otros productos de propiedad intelectual específicos para I+D;Total;7,919 1.1) By origin of the funds: Own funds;Fewer than 250 employees;385,847 1.1) By origin of the funds: Own funds;250 or more employees;105,066 1.1) By origin of the funds: Own funds;Total;490,913 1.2) By origin of the funds: From companies;Fewer than 250 employees;53,140 1.2) By origin of the funds: From companies;250 or more employees;29,409 1.2) By origin of the funds: From companies;Total;82,548 1.3) By origin of the funds: Public Administration funds;Fewer than 250 employees;64,168 1.3) By origin of the funds: Public Administration funds;250 or more employees;32,641 1.3) By origin of the funds: Public Administration funds;Total;96,809 1.4) By origin of the funds: From Universities;Fewer than 250 employees;197 1.4) By origin of the funds: From Universities;250 or more employees;0 1.4) By origin of the funds: From Universities;Total;197 1.5) By origin of the funds: From non profit private institutions;Fewer than 250 employees;588 1.5) By origin of the funds: From non profit private institutions;250 or more employees;4,177 1.5) By origin of the funds: From non profit private institutions;Total;4,766 1.6) By origin of the funds: Foreign funds;Fewer than 250 employees;54,244 1.6) By origin of the funds: Foreign funds;250 or more employees;39,954 1.6) By origin of the funds: Foreign funds;Total;94,197 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;68,331 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;51,951 Purchase of R&D services in biotechnology (thousands of euros);Total;120,281 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;22,667 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;46,897 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;69,564 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;45,664 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;5,054 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;50,718 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;47 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;23 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;45 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;11 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;19 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;15 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;37 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;29 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;37 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;53 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;39 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;52 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;20 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;20 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;17 % Companies that have requested biotechnology patents in Biotechnology;Total;15 Number of patents requested;Fewer than 250 employees;525 Number of patents requested;250 or more employees;156 Number of patents requested;Total;681 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;24.9 % Companies with income of an international origin related to biotechnological activities;250 or more employees;18.4 % Companies with income of an international origin related to biotechnological activities;Total;24.3 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;6.00 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;1.00 % Turnover representing income of an international origin related to biotechnological activities;Total;1.00 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;45.20 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;73.10 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;59.60 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;54.80 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;26.90 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;40.40 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;89.00 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;72.50 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;80.40 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;7.50 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;24.90 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;16.50 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;2.20 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;2.30 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;2.20 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;1.40 % Income of an international origin related with activities according to the classification: Other;250 or more employees;0.40 % Income of an international origin related with activities according to the classification: Other;Total;0.90