Main variables;Fields of operation;Total Companies that perform R+D in Biotechnology;Total 2019;1.399 Companies that perform R+D in Biotechnology;Companies;1.198 Companies that perform R+D in Biotechnology;P.A.;122 Companies that perform R+D in Biotechnology;Higher Education;66 Companies that perform R+D in Biotechnology;PNPI;13 %Companies according to biotechnology used: Genetic code;Total 2019;40,8 %Companies according to biotechnology used: Genetic code;Companies;33,3 %Companies according to biotechnology used: Genetic code;P.A.;88,5 %Companies according to biotechnology used: Genetic code;Higher Education;87,9 %Companies according to biotechnology used: Genetic code;PNPI;38,5 %Companies according to biotechnology used: Functional Companies;Total 2019;46,7 %Companies according to biotechnology used: Functional Companies;Companies;39,8 %Companies according to biotechnology used: Functional Companies;P.A.;88,5 %Companies according to biotechnology used: Functional Companies;Higher Education;92,4 %Companies according to biotechnology used: Functional Companies;PNPI;53,8 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total 2019;31,5 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Companies;24,2 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;P.A.;73 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Higher Education;83,3 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;PNPI;53,8 %Companies according to biotechnology used: Bioprocesses;Total 2019;52,4 %Companies according to biotechnology used: Bioprocesses;Companies;49,6 %Companies according to biotechnology used: Bioprocesses;P.A.;59 %Companies according to biotechnology used: Bioprocesses;Higher Education;92,4 %Companies according to biotechnology used: Bioprocesses;PNPI;46,2 %Companies according to biotechnology used: Sub-cellular organisms;Total 2019;14,4 %Companies according to biotechnology used: Sub-cellular organisms;Companies;6,7 %Companies according to biotechnology used: Sub-cellular organisms;P.A.;56,6 %Companies according to biotechnology used: Sub-cellular organisms;Higher Education;72,7 %Companies according to biotechnology used: Sub-cellular organisms;PNPI;38,5 %Companies according to biotechnology used: Bio-computing;Total 2019;30,8 %Companies according to biotechnology used: Bio-computing;Companies;23,9 %Companies according to biotechnology used: Bio-computing;P.A.;71,3 %Companies according to biotechnology used: Bio-computing;Higher Education;84,8 %Companies according to biotechnology used: Bio-computing;PNPI;15,4 %Companies according to biotechnology used: Nanobiotechnology;Total 2019;17,4 %Companies according to biotechnology used: Nanobiotechnology;Companies;11,2 %Companies according to biotechnology used: Nanobiotechnology;P.A.;50,8 %Companies according to biotechnology used: Nanobiotechnology;Higher Education;71,2 %Companies according to biotechnology used: Nanobiotechnology;PNPI;7,7 %Companies according to biotechnology used: Other;Total 2019;13,9 %Companies according to biotechnology used: Other;Companies;14,6 %Companies according to biotechnology used: Other;P.A.;7,4 %Companies according to biotechnology used: Other;Higher Education;15,2 %Companies according to biotechnology used: Other;PNPI;7,7 Companies in which biotechnology activities are: Main and/or exclusive;Total 2019;685 Companies in which biotechnology activities are: Main and/or exclusive;Companies;644 Companies in which biotechnology activities are: Main and/or exclusive;P.A.;33 Companies in which biotechnology activities are: Main and/or exclusive;Higher Education;2 Companies in which biotechnology activities are: Main and/or exclusive;PNPI;6 Companies in which biotechnology activities are: A secondary line of business;Total 2019;253 Companies in which biotechnology activities are: A secondary line of business;Companies;171 Companies in which biotechnology activities are: A secondary line of business;P.A.;37 Companies in which biotechnology activities are: A secondary line of business;Higher Education;43 Companies in which biotechnology activities are: A secondary line of business;PNPI;2 Companies in which biotechnology activities are: A tool necessary for production;Total 2019;461 Companies in which biotechnology activities are: A tool necessary for production;Companies;383 Companies in which biotechnology activities are: A tool necessary for production;P.A.;52 Companies in which biotechnology activities are: A tool necessary for production;Higher Education;21 Companies in which biotechnology activities are: A tool necessary for production;PNPI;5 %Companies by field(s) of ultimate application of biotechnology use: Human health;Total 2019;52 %Companies by field(s) of ultimate application of biotechnology use: Human health;Companies;47 %Companies by field(s) of ultimate application of biotechnology use: Human health;P.A.;77 %Companies by field(s) of ultimate application of biotechnology use: Human health;Higher Education;91 %Companies by field(s) of ultimate application of biotechnology use: Human health;PNPI;62 %Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total 2019;21 %Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Companies;19 %Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;P.A.;16 %Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Higher Education;68 %Companies by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;PNPI;8 %Companies by field(s) of ultimate application of biotechnology use: Food products;Total 2019;33 %Companies by field(s) of ultimate application of biotechnology use: Food products;Companies;33 %Companies by field(s) of ultimate application of biotechnology use: Food products;P.A.;19 %Companies by field(s) of ultimate application of biotechnology use: Food products;Higher Education;80 %Companies by field(s) of ultimate application of biotechnology use: Food products;PNPI;8 %Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:;Total 2019;26 %Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:;Companies;24 %Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:;P.A.;20 %Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:;Higher Education;71 %Companies by field(s) of ultimate application of biotechnology use: Agriculture and forest production:;PNPI;23 %Companies by field(s) of ultimate application of biotechnology use: Environment;Total 2019;18 %Companies by field(s) of ultimate application of biotechnology use: Environment;Companies;15 %Companies by field(s) of ultimate application of biotechnology use: Environment;P.A.;21 %Companies by field(s) of ultimate application of biotechnology use: Environment;Higher Education;74 %Companies by field(s) of ultimate application of biotechnology use: Environment;PNPI;15 %Companies by field(s) of ultimate application of biotechnology use: Industry;Total 2019;16 %Companies by field(s) of ultimate application of biotechnology use: Industry;Companies;13 %Companies by field(s) of ultimate application of biotechnology use: Industry;P.A.;13 %Companies by field(s) of ultimate application of biotechnology use: Industry;Higher Education;70 %Companies by field(s) of ultimate application of biotechnology use: Industry;PNPI;8 Personnel in R&D in biotechnology (no. of persons);Total 2019;43.523 Personnel in R&D in biotechnology (no. of persons);Companies;13.615 Personnel in R&D in biotechnology (no. of persons);P.A.;14.682 Personnel in R&D in biotechnology (no. of persons);Higher Education;15.063 Personnel in R&D in biotechnology (no. of persons);PNPI;163 Personnel in R&D in biotechnology (no. of persons): Researchers;Total 2019;28.702 Personnel in R&D in biotechnology (no. of persons): Researchers;Companies;7.436 Personnel in R&D in biotechnology (no. of persons): Researchers;P.A.;9.191 Personnel in R&D in biotechnology (no. of persons): Researchers;Higher Education;11.968 Personnel in R&D in biotechnology (no. of persons): Researchers;PNPI;107 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total 2019;14.820 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Companies;6.178 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;P.A.;5.491 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Higher Education;3.095 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;PNPI;56 Personnel in R&D in biotechnology (no. of persons): women;Total 2019;24.516 Personnel in R&D in biotechnology (no. of persons): women;Companies;7.639 Personnel in R&D in biotechnology (no. of persons): women;P.A.;9.277 Personnel in R&D in biotechnology (no. of persons): women;Higher Education;7.494 Personnel in R&D in biotechnology (no. of persons): women;PNPI;106 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total 2019;15.356 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Companies;4.095 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;P.A.;5.444 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Higher Education;5.753 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;PNPI;64 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total 2019;9.160 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Companies;3.544 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;P.A.;3.833 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Higher Education;1.741 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;PNPI;42 Personnel in R&D in biotechnology (FTE);Total 2019;29.655,1 Personnel in R&D in biotechnology (FTE);Companies;9.365,2 Personnel in R&D in biotechnology (FTE);P.A.;11.013,2 Personnel in R&D in biotechnology (FTE);Higher Education;9.177,3 Personnel in R&D in biotechnology (FTE);PNPI;99,4 Personnel in R&D in biotechnology (FTE): Researchers;Total 2019;19.150,3 Personnel in R&D in biotechnology (FTE): Researchers;Companies;5.410,6 Personnel in R&D in biotechnology (FTE): Researchers;P.A.;6.546,6 Personnel in R&D in biotechnology (FTE): Researchers;Higher Education;7.128,5 Personnel in R&D in biotechnology (FTE): Researchers;PNPI;64,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total 2019;10.504,8 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Companies;3.954,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;P.A.;4.466,6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Higher Education;2.048,8 Personnel in R&D in biotechnology (FTE): Technicians and assistants;PNPI;34,8 Personnel in R&D in biotechnology (FTE): women;Total 2019;16.997,1 Personnel in R&D in biotechnology (FTE): women;Companies;5.385,8 Personnel in R&D in biotechnology (FTE): women;P.A.;6.959,9 Personnel in R&D in biotechnology (FTE): women;Higher Education;4.581,4 Personnel in R&D in biotechnology (FTE): women;PNPI;70 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total 2019;10.349,2 Personnel in R&D in biotechnology (FTE): (women) Researchers;Companies;3.032,9 Personnel in R&D in biotechnology (FTE): (women) Researchers;P.A.;3.876,1 Personnel in R&D in biotechnology (FTE): (women) Researchers;Higher Education;3.397,2 Personnel in R&D in biotechnology (FTE): (women) Researchers;PNPI;43 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total 2019;6.647,9 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Companies;2.352,9 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;P.A.;3.083,8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Higher Education;1.184,2 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;PNPI;27 Internal expenditure on R&D (thousands of euros);Total 2019;2.040.323 Internal expenditure on R&D (thousands of euros);Companies;940.230 Internal expenditure on R&D (thousands of euros);P.A.;652.393 Internal expenditure on R&D (thousands of euros);Higher Education;442.089 Internal expenditure on R&D (thousands of euros);PNPI;5.611 1) By nature of the expense: Current expenses;Total 2019;1.899.869 1) By nature of the expense: Current expenses;Companies;871.813 1) By nature of the expense: Current expenses;P.A.;608.579 1) By nature of the expense: Current expenses;Higher Education;413.960 1) By nature of the expense: Current expenses;PNPI;5.517 1.1) Remuneration to researchers;Total 2019;776.880 1.1) Remuneration to researchers;Companies;284.936 1.1) Remuneration to researchers;P.A.;242.168 1.1) Remuneration to researchers;Higher Education;247.973 1.1) Remuneration to researchers;PNPI;1.802 1.2) Remuneration to technicians and assistants;Total 2019;333.017 1.2) Remuneration to technicians and assistants;Companies;148.254 1.2) Remuneration to technicians and assistants;P.A.;118.062 1.2) Remuneration to technicians and assistants;Higher Education;65.769 1.2) Remuneration to technicians and assistants;PNPI;931 1.3) Other current expenses;Total 2019;789.972 1.3) Other current expenses;Companies;438.623 1.3) Other current expenses;P.A.;248.348 1.3) Other current expenses;Higher Education;100.217 1.3) Other current expenses;PNPI;2.784 2) By nature of the expense: Capital expenses;Total 2019;140.454 2) By nature of the expense: Capital expenses;Companies;68.417 2) By nature of the expense: Capital expenses;P.A.;43.814 2) By nature of the expense: Capital expenses;Higher Education;28.129 2) By nature of the expense: Capital expenses;PNPI;94 2.1) Land and buildings;Total 2019;30.677 2.1) Land and buildings;Companies;11.763 2.1) Land and buildings;P.A.;11.874 2.1) Land and buildings;Higher Education;7.040 2.1) Land and buildings;PNPI;0 2.2) Equipment and instruments;Total 2019;90.306 2.2) Equipment and instruments;Companies;39.641 2.2) Equipment and instruments;P.A.;31.009 2.2) Equipment and instruments;Higher Education;19.567 2.2) Equipment and instruments;PNPI;89 2.3) Acquisition of specific R+D software;Total 2019;4.900 2.3) Acquisition of specific R+D software;Companies;2.831 2.3) Acquisition of specific R+D software;P.A.;757 2.3) Acquisition of specific R+D software;Higher Education;1.310 2.3) Acquisition of specific R+D software;PNPI;3 2.4) Otros productos de propiedad intelectual específicos para I+D;Total 2019;14.571 2.4) Otros productos de propiedad intelectual específicos para I+D;Companies;14.183 2.4) Otros productos de propiedad intelectual específicos para I+D;P.A.;173 2.4) Otros productos de propiedad intelectual específicos para I+D;Higher Education;212 2.4) Otros productos de propiedad intelectual específicos para I+D;PNPI;2 1.1) By origin of the funds: Own funds;Total 2019;742.583 1.1) By origin of the funds: Own funds;Companies;577.287 1.1) By origin of the funds: Own funds;P.A.;78.505 1.1) By origin of the funds: Own funds;Higher Education;86.280 1.1) By origin of the funds: Own funds;PNPI;511 1.2) By origin of the funds: From companies;Total 2019;268.227 1.2) By origin of the funds: From companies;Companies;142.672 1.2) By origin of the funds: From companies;P.A.;96.507 1.2) By origin of the funds: From companies;Higher Education;28.164 1.2) By origin of the funds: From companies;PNPI;884 1.3) By origin of the funds: Public Administration funds;Total 2019;783.942 1.3) By origin of the funds: Public Administration funds;Companies;102.630 1.3) By origin of the funds: Public Administration funds;P.A.;396.610 1.3) By origin of the funds: Public Administration funds;Higher Education;282.374 1.3) By origin of the funds: Public Administration funds;PNPI;2.327 1.4) By origin of the funds: From Universities;Total 2019;2.785 1.4) By origin of the funds: From Universities;Companies;457 1.4) By origin of the funds: From Universities;P.A.;1.190 1.4) By origin of the funds: From Universities;Higher Education;1.138 1.4) By origin of the funds: From Universities;PNPI;0 1.5) By origin of the funds: From non profit private institutions;Total 2019;30.232 1.5) By origin of the funds: From non profit private institutions;Companies;9.631 1.5) By origin of the funds: From non profit private institutions;P.A.;13.309 1.5) By origin of the funds: From non profit private institutions;Higher Education;5.740 1.5) By origin of the funds: From non profit private institutions;PNPI;1.553 1.6) By origin of the funds: Foreign funds;Total 2019;212.555 1.6) By origin of the funds: Foreign funds;Companies;107.553 1.6) By origin of the funds: Foreign funds;P.A.;66.273 1.6) By origin of the funds: Foreign funds;Higher Education;38.392 1.6) By origin of the funds: Foreign funds;PNPI;336 Purchase of services R & D in Biotechnology to (thousands of euros);Total 2019;133.151 Purchase of services R & D in Biotechnology to (thousands of euros);Companies;114.839 Purchase of services R & D in Biotechnology to (thousands of euros);P.A.;12.728 Purchase of services R & D in Biotechnology to (thousands of euros);Higher Education;5.216 Purchase of services R & D in Biotechnology to (thousands of euros);PNPI;368 Purchase of services R & D in Biotechnology to (thousands of euros): in Spain;Total 2019;85.933 Purchase of services R & D in Biotechnology to (thousands of euros): in Spain;Companies;69.258 Purchase of services R & D in Biotechnology to (thousands of euros): in Spain;P.A.;11.630 Purchase of services R & D in Biotechnology to (thousands of euros): in Spain;Higher Education;4.727 Purchase of services R & D in Biotechnology to (thousands of euros): in Spain;PNPI;318 Purchase of services R & D in Biotechnology to (thousands of euros): Abroad;Total 2019;47.219 Purchase of services R & D in Biotechnology to (thousands of euros): Abroad;Companies;45.581 Purchase of services R & D in Biotechnology to (thousands of euros): Abroad;P.A.;1.098 Purchase of services R & D in Biotechnology to (thousands of euros): Abroad;Higher Education;489 Purchase of services R & D in Biotechnology to (thousands of euros): Abroad;PNPI;51 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total 2019;44,2 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Companies;41,8 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;P.A.;57,4 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Higher Education;56,1 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;PNPI;76,9 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total 2019;11,3 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Companies;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;P.A.;2,5 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Higher Education;12,1 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;PNPI;23,1 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total 2019;16,8 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Companies;13,1 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;P.A.;39,3 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Higher Education;40,9 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;PNPI;30,8 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total 2019;13,4 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Companies;10,7 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;P.A.;28,7 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Higher Education;33,3 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;PNPI;23,1 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total 2019;18,1 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Companies;15,1 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;P.A.;32,8 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Higher Education;42,4 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;PNPI;30,8 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels;Total 2019;18 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels;Companies;16 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels;P.A.;30 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels;Higher Education;41 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and marketing channels;PNPI;23 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total 2019;15,2 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Companies;15,9 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;P.A.;9 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Higher Education;10,6 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;PNPI;38,5 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total 2019;37 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Companies;37 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;P.A.;41 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Higher Education;36 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;PNPI;39 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total 2019;51,9 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Companies;50,7 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;P.A.;57,4 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Higher Education;63,6 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;PNPI;53,8 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total 2019;19,1 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Companies;19 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;P.A.;20,5 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Higher Education;16,7 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;PNPI;30,8 %Companies that have requested biotechnology patents in Biotechnology;Total 2019;23,7 %Companies that have requested biotechnology patents in Biotechnology;Companies;18,3 %Companies that have requested biotechnology patents in Biotechnology;P.A.;53,3 %Companies that have requested biotechnology patents in Biotechnology;Higher Education;69,7 %Companies that have requested biotechnology patents in Biotechnology;PNPI;7,7 Number of patents requested;Total 2019;1.846 Number of patents requested;Companies;643 Number of patents requested;P.A.;667 Number of patents requested;Higher Education;535 Number of patents requested;PNPI;1