Statistics on Biotechnology Use Results by fields of operation Business Sector Biotechnology indicators by company size. Unidades: specified in variables ,Fewer than 250 employees,250 or more employees,Total 2021, No. of companies carrying out R&D in Biotechnology,1.155,145,1.299, %Companies according to biotechnology used: Genetic code,29,7,39,5,30,8, %Companies according to biotechnology used: Functional units,37,4,46,5,38,4, %Companies according to biotechnology used: Cellular and tissue culturing and engineering,20,1,33,3,21,5, %Companies according to biotechnology used: Bioprocesses,49,2,63,2,50,8, %Companies according to biotechnology used: Sub-cellular organisms,7,5,15,9,8,5, %Companies according to biotechnology used: Bio-computing,23,7,26,4,24, %Companies according to biotechnology used: Nanobiotechnology,12,2,11,1,12,1, %Companies according to biotechnology used: Other,17,2,14,6,16,9, Companies in which biotechnology activities are: Main and/or exclusive,544,15,559, Companies in which biotechnology activities are: A secondary line of business,191,39,230, Companies in which biotechnology activities are: A tool necessary for production,420,90,510, %Company by field(s) of ultimate application of biotechnology use: Human Health,45,9,42,3,45,5, %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture,15,9,12,5,15,5, %Company by field(s) of ultimate application of biotechnology use: Food products,31,9,35,5,32,3, %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production,24,1,20,8,23,8, %Company by field(s) of ultimate application of biotechnology use: Environment,16,12,5,15,6, %Company by field(s) of ultimate application of biotechnology use: Industry,13,9,12,5,13,7, Personnel in R&D in biotechnology (no. of persons),9.560,6.190,15.750, Personnel in R&D in biotechnology (no. of persons): Research personnel,5.506,2.874,8.379, Personnel in R&D in biotechnology (no. of persons): Technical and auxiliary personnel,4.055,3.316,7.371, Personnel in R&D in biotechnology (no. of persons). Women,4.963,3.748,8.711, Personnel in R&D in biotechnology (no. of persons). Women: Research personnel,2.838,1.673,4.510, Personnel in R&D in biotechnology (no. of persons). Women: Technical and auxiliary personnel,2.125,2.075,4.200, Personnel in R&D in biotechnology (FTE),6.711,4.817,6,11.528,6, Personnel in R&D in biotechnology (FTE): Research personnel,4.162,2,2.180,5,6.342,7, Personnel in R&D in biotechnology (FTE): Technical and auxiliary personnel,2.548,8,2.637,1,5.185,9, Personnel in R&D in biotechnology (FTE). Women,3.575,2,2.964,6,6.539,7, Personnel in R&D in biotechnology (FTE). Women: Research personnel,2.167,4,1.288,4,3.455,7, Personnel in R&D in biotechnology (FTE). Women: Technical and auxiliary personnel,1.407,8,1.676,2,3.084, Internal expenditure on R&D (thousands of euros),593.445,445.137,1.038.582, 1) By nature of the expense: Current expenses,531.987,408.103,940.091, 1.1) Remuneration to research personnel,194.798,126.772,321.570, 1.2) Remuneration to technical and auxiliary personnel,91.565,103.271,194.836, 1.3) Other current expenses,245.624,178.061,423.685, 2) By nature of the expense: Capital expenses,61.458,37.033,98.492, 2.1) Land and buildings,7.788,2.411,10.199, 2.2) Equipment and instruments,40.235,32.349,72.584, 2.3) Acquisition of specific R&D software,3.600,2.121,5.721, 2.4) Otros productos de propiedad intelectual específicos para I+D,9.835,152,9.987, 1.1) By origin of the funds: Own funds,403.266,308.222,711.488, 1.2) By origin of the funds: From companies,75.949,45.789,121.738, 1.3) By origin of the funds: Public Administration funds,76.924,30.552,107.477, 1.4) By origin of the funds: From Universities,192,0,192, 1.5) By origin of the funds: From non profit private institutions,1.543,9.213,10.756, 1.6) By origin of the funds: Foreign funds,35.570,51.360,86.931, Purchase of R&D services in biotechnology (thousands of euros),75.599,69.958,145.557, Purchase of R&D services in biotechnology (thousands of euros): In Spain,53.934,41.981,95.915, Purchase of R&D services in biotechnology (thousands of euros): Abroad,21.665,27.977,49.642, %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital,42,3,23,7,40,2, %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information,13,1,13,9,13,2, %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources,19,4,16,19, %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain,11,15,3,11,5, %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets,16,5,10,4,15,9, %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels,17,8,10,4,17, %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception,16,1,19,5,16,4, %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements,41,2,34,8,40,5, %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost,56,1,46,5,55, %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting,22,3,18,7,21,9, % Companies with income of an international origin related to biotechnological activities,24,2,18,1,23,5, % Turnover representing income of an international origin related to biotechnological activities,10,6,0,8,1,9, % Income of an international origin related to biotechnological activities distributed in: Income received from the EU,56,69,8,61,6, % Income of an international origin related to biotechnological activities distributed in: Income received from other countries,44,30,2,38,4, % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services,93,8,78,7,87,6, % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain,4,9,19,6,10,9, % Income of an international origin related with activities according to the classification: Operating source abroad,0,6,1,8,1,1, % Income of an international origin related with activities according to the classification: Other,0,6,0,0,4, Notas: '.'=numeric piece of data equal to zero not resulting from rounding FTE: Full Time Equivalent Fuente: National Statistics Institute