Indicator type Branch of activity Total Number of companies carrying out R&D in Biotechnology Total companies 1,602 Number of companies carrying out R&D in Biotechnology Agriculture 106 Number of companies carrying out R&D in Biotechnology Industry and Construction 414 Number of companies carrying out R&D in Biotechnology Services 1,082 % Companies by type of biotechnology used: Genetic Code Total companies 28.8 % Companies by type of biotechnology used: Genetic Code Agriculture 21.8 % Companies by type of biotechnology used: Genetic Code Industry and Construction 16.3 % Companies by type of biotechnology used: Genetic Code Services 34.3 % Companies by type of biotechnology used: Functional Units Total companies 38.9 % Companies by type of biotechnology used: Functional Units Agriculture 12.6 % Companies by type of biotechnology used: Functional Units Industry and Construction 34.9 % Companies by type of biotechnology used: Functional Units Services 43.0 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Total companies 21.5 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Agriculture 9.9 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Industry and Construction 19.3 % Companies by type of biotechnology used: Cell and Tissue Culture and Engineering Services 23.5 % Companies by type of biotechnology used: Bioprocesses Total companies 49.5 % Companies by type of biotechnology used: Bioprocesses Agriculture 44.1 % Companies by type of biotechnology used: Bioprocesses Industry and Construction 73.7 % Companies by type of biotechnology used: Bioprocesses Services 40.8 % Companies by type of biotechnology used: Subcellular Organisms Total companies 8.7 % Companies by type of biotechnology used: Subcellular Organisms Agriculture 1.0 % Companies by type of biotechnology used: Subcellular Organisms Industry and Construction 6.3 % Companies by type of biotechnology used: Subcellular Organisms Services 10.3 % Companies by type of biotechnology used: Bioinformatics Total companies 26.9 % Companies by type of biotechnology used: Bioinformatics Agriculture 4.8 % Companies by type of biotechnology used: Bioinformatics Industry and Construction 11.9 % Companies by type of biotechnology used: Bioinformatics Services 34.7 % Companies by type of biotechnology used: Nanobiotechnology Total companies 11.8 % Companies by type of biotechnology used: Nanobiotechnology Agriculture 1.3 % Companies by type of biotechnology used: Nanobiotechnology Industry and Construction 6.0 % Companies by type of biotechnology used: Nanobiotechnology Services 15.1 % Companies by type of biotechnology used: Other Total companies 18.0 % Companies by type of biotechnology used: Other Agriculture 35.0 % Companies by type of biotechnology used: Other Industry and Construction 12.2 % Companies by type of biotechnology used: Other Services 18.6 Companies in which biotechnology activities are: Main and/or exclusive Total companies 773 Companies in which biotechnology activities are: Main and/or exclusive Agriculture 23 Companies in which biotechnology activities are: Main and/or exclusive Industry and Construction 106 Companies in which biotechnology activities are: Main and/or exclusive Services 645 Companies in which biotechnology activities are: A secondary business line Total companies 279 Companies in which biotechnology activities are: A secondary business line Agriculture 27 Companies in which biotechnology activities are: A secondary business line Industry and Construction 94 Companies in which biotechnology activities are: A secondary business line Services 157 Companies in which biotechnology activities are: A necessary tool for production Total companies 550 Companies in which biotechnology activities are: A necessary tool for production Agriculture 56 Companies in which biotechnology activities are: A necessary tool for production Industry and Construction 214 Companies in which biotechnology activities are: A necessary tool for production Services 281 % Companies by final application areas of biotechnology use: Human Health Total companies 48.4 % Companies by final application areas of biotechnology use: Human Health Agriculture 1.9 % Companies by final application areas of biotechnology use: Human Health Industry and Construction 25.8 % Companies by final application areas of biotechnology use: Human Health Services 61.5 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Total companies 19.1 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Agriculture 29.9 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Industry and Construction 16.2 % Companies by final application areas of biotechnology use: Animal Health and Aquaculture Services 19.2 % Companies by final application areas of biotechnology use: Food Products Total companies 28.9 % Companies by final application areas of biotechnology use: Food Products Agriculture 32.9 % Companies by final application areas of biotechnology use: Food Products Industry and Construction 46.0 % Companies by final application areas of biotechnology use: Food Products Services 22.0 % Companies by final application areas of biotechnology use: Agriculture and Forestry Total companies 24.8 % Companies by final application areas of biotechnology use: Agriculture and Forestry Agriculture 61.7 % Companies by final application areas of biotechnology use: Agriculture and Forestry Industry and Construction 24.5 % Companies by final application areas of biotechnology use: Agriculture and Forestry Services 21.3 % Companies by final application areas of biotechnology use: Environment Total companies 18.2 % Companies by final application areas of biotechnology use: Environment Agriculture 14.5 % Companies by final application areas of biotechnology use: Environment Industry and Construction 18.2 % Companies by final application areas of biotechnology use: Environment Services 18.6 % Companies by final application areas of biotechnology use: Industry Total companies 13.5 % Companies by final application areas of biotechnology use: Industry Agriculture 5.8 % Companies by final application areas of biotechnology use: Industry Industry and Construction 14.9 % Companies by final application areas of biotechnology use: Industry Services 13.7 R&D personnel in Biotechnology (PP) Total companies 19,307 R&D personnel in Biotechnology (PP) Agriculture 1,164 R&D personnel in Biotechnology (PP) Industry and Construction 5,254 R&D personnel in Biotechnology (PP) Services 12,889 R&D personnel in Biotechnology (PP): Research personnel Total companies 10,779 R&D personnel in Biotechnology (PP): Research personnel Agriculture 310 R&D personnel in Biotechnology (PP): Research personnel Industry and Construction 2,465 R&D personnel in Biotechnology (PP): Research personnel Services 8,004 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Total companies 8,528 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Agriculture 854 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Industry and Construction 2,789 R&D personnel in Biotechnology (PP): Technical and auxiliary personnel Services 4,885 R&D personnel in Biotechnology (PP). Women Total companies 11,155 R&D personnel in Biotechnology (PP). Women Agriculture 562 R&D personnel in Biotechnology (PP). Women Industry and Construction 2,961 R&D personnel in Biotechnology (PP). Women Services 7,632 R&D personnel in Biotechnology (PP). Women: Research personnel Total companies 5,934 R&D personnel in Biotechnology (PP). Women: Research personnel Agriculture 121 R&D personnel in Biotechnology (PP). Women: Research personnel Industry and Construction 1,312 R&D personnel in Biotechnology (PP). Women: Research personnel Services 4,500 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Total companies 5,222 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Agriculture 441 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Industry and Construction 1,649 R&D personnel in Biotechnology (PP). Women: Technical and auxiliary personnel Services 3,132 R&D personnel in Biotechnology (FTE) Total companies 14,093.7 R&D personnel in Biotechnology (FTE) Agriculture 773.9 R&D personnel in Biotechnology (FTE) Industry and Construction 3,606.1 R&D personnel in Biotechnology (FTE) Services 9,713.7 R&D personnel in Biotechnology (FTE): Research personnel Total companies 8,073.8 R&D personnel in Biotechnology (FTE): Research personnel Agriculture 219.3 R&D personnel in Biotechnology (FTE): Research personnel Industry and Construction 1,751.9 R&D personnel in Biotechnology (FTE): Research personnel Services 6,102.6 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Total companies 6,019.9 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Agriculture 554.6 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Industry and Construction 1,854.2 R&D personnel in Biotechnology (FTE): Technical and auxiliary personnel Services 3,611.1 R&D personnel in Biotechnology (FTE). Women Total companies 8,305.8 R&D personnel in Biotechnology (FTE). Women Agriculture 401.9 R&D personnel in Biotechnology (FTE). Women Industry and Construction 2,140.3 R&D personnel in Biotechnology (FTE). Women Services 5,763.6 R&D personnel in Biotechnology (FTE). Women: Research personnel Total companies 4,482.6 R&D personnel in Biotechnology (FTE). Women: Research personnel Agriculture 94.4 R&D personnel in Biotechnology (FTE). Women: Research personnel Industry and Construction 954.2 R&D personnel in Biotechnology (FTE). Women: Research personnel Services 3,434.0 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Total companies 3,823.2 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Agriculture 307.6 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Industry and Construction 1,186.0 R&D personnel in Biotechnology (FTE). Women: Technical and auxiliary personnel Services 2,329.6 Expenditure on internal R&D in Biotechnology (thousands of euros) Total companies 1,462,695 Expenditure on internal R&D in Biotechnology (thousands of euros) Agriculture 50,039 Expenditure on internal R&D in Biotechnology (thousands of euros) Industry and Construction 460,648 Expenditure on internal R&D in Biotechnology (thousands of euros) Services 952,007 1) By type of expenditure: Current expenditure Total companies 1,347,574 1) By type of expenditure: Current expenditure Agriculture 47,888 1) By type of expenditure: Current expenditure Industry and Construction 428,926 1) By type of expenditure: Current expenditure Services 870,760 1.1) Labour expenditure of research personnel Total companies 470,714 1.1) Labour expenditure of research personnel Agriculture 13,630 1.1) Labour expenditure of research personnel Industry and Construction 137,896 1.1) Labour expenditure of research personnel Services 319,187 1.2) Labour expenditure of technical and auxiliary personnel Total companies 258,791 1.2) Labour expenditure of technical and auxiliary personnel Agriculture 18,864 1.2) Labour expenditure of technical and auxiliary personnel Industry and Construction 97,459 1.2) Labour expenditure of technical and auxiliary personnel Services 142,468 1.3) Other current expenditure Total companies 618,069 1.3) Other current expenditure Agriculture 15,394 1.3) Other current expenditure Industry and Construction 193,571 1.3) Other current expenditure Services 409,105 2) By type of expenditure: Capital expenditure Total companies 115,121 2) By type of expenditure: Capital expenditure Agriculture 2,151 2) By type of expenditure: Capital expenditure Industry and Construction 31,722 2) By type of expenditure: Capital expenditure Services 81,247 2.1) Land and buildings Total companies 21,877 2.1) Land and buildings Agriculture 787 2.1) Land and buildings Industry and Construction 10,015 2.1) Land and buildings Services 11,075 2.2) Equipment and tools Total companies 54,592 2.2) Equipment and tools Agriculture 1,251 2.2) Equipment and tools Industry and Construction 18,732 2.2) Equipment and tools Services 34,608 2.3) Acquisition of specific R&D software Total companies 4,673 2.3) Acquisition of specific R&D software Agriculture 70 2.3) Acquisition of specific R&D software Industry and Construction 1,097 2.3) Acquisition of specific R&D software Services 3,506 2.4) Other R&D-specific IP products Total companies 33,978 2.4) Other R&D-specific IP products Agriculture 43 2.4) Other R&D-specific IP products Industry and Construction 1,877 2.4) Other R&D-specific IP products Services 32,058 1.1) By origin of funds: Own funds Total companies 1,013,505 1.1) By origin of funds: Own funds Agriculture 41,821 1.1) By origin of funds: Own funds Industry and Construction 403,162 1.1) By origin of funds: Own funds Services 568,522 1.2) By origin of funds: Funds from the Business sector Total companies 206,072 1.2) By origin of funds: Funds from the Business sector Agriculture 4,418 1.2) By origin of funds: Funds from the Business sector Industry and Construction 26,556 1.2) By origin of funds: Funds from the Business sector Services 175,098 1.3) By origin of funds: Funds from the Public Administration sector Total companies 158,706 1.3) By origin of funds: Funds from the Public Administration sector Agriculture 2,963 1.3) By origin of funds: Funds from the Public Administration sector Industry and Construction 21,927 1.3) By origin of funds: Funds from the Public Administration sector Services 133,817 1.4) By origin of funds: Funds from the Higher Education sector Total companies 615 1.4) By origin of funds: Funds from the Higher Education sector Agriculture 127 1.4) By origin of funds: Funds from the Higher Education sector Industry and Construction 18 1.4) By origin of funds: Funds from the Higher Education sector Services 470 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Total companies 9,828 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Agriculture 0 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Industry and Construction 0 1.5) By origin of funds: Funds from the Private Non-Profit Institutions sector Services 9,828 1.6) By origin of funds: Funds from the rest of the world Total companies 73,969 1.6) By origin of funds: Funds from the rest of the world Agriculture 711 1.6) By origin of funds: Funds from the rest of the world Industry and Construction 8,986 1.6) By origin of funds: Funds from the rest of the world Services 64,272 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Total companies 96,238 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Agriculture 691 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Industry and Construction 51,441 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros) Services 44,106 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Total companies 65,364 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Agriculture 302 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Industry and Construction 42,505 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In Spain Services 22,557 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Total companies 30,874 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Agriculture 389 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Industry and Construction 8,936 Purchase of R&D services (external R&D) in Biotechnology (thousands of euros): In the rest of the world Services 21,549 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Total companies 46.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Agriculture 34.5 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Industry and Construction 35.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to capital Services 51.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Total companies 17.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Agriculture 21.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Industry and Construction 19.8 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to technology/information Services 15.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Total companies 25.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Agriculture 31.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Industry and Construction 29.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Access to human resources Services 24.2 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Total companies 13.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Agriculture 13.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Industry and Construction 12.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Disconnection from the value chain Services 13.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Total companies 18.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Agriculture 14.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Industry and Construction 11.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of access to international markets Services 21.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Total companies 17.3 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Agriculture 10.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Industry and Construction 11.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Lack of distribution and marketing channels Services 20.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Total companies 20.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Agriculture 20.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Industry and Construction 17.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Public acceptance/perception Services 20.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Total companies 47.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Agriculture 43.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Industry and Construction 43.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Legal and regulatory requirements Services 49.1 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Total companies 53.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Agriculture 48.9 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Industry and Construction 53.0 % Companies that consider the following obstacles to the development of biotechnologies as very important: Time/cost Services 54.4 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Total companies 21.6 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Agriculture 23.7 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Industry and Construction 17.8 % Companies that consider the following obstacles to the development of biotechnologies as very important: Difficult access to patenting Services 22.9 % Companies with international revenues related to biotechnology activities Total companies 22.2 % Companies with international revenues related to biotechnology activities Agriculture 8.1 % Companies with international revenues related to biotechnology activities Industry and Construction 24.4 % Companies with international revenues related to biotechnology activities Services 22.7 % Companies representing international revenues related to biotechnology activities Total companies 2.2 % Companies representing international revenues related to biotechnology activities Agriculture 0.6 % Companies representing international revenues related to biotechnology activities Industry and Construction 2.1 % Companies representing international revenues related to biotechnology activities Services 2.9 % International revenues related to biotechnology activities distributed in: Revenues from the EU Total companies 55.2 % International revenues related to biotechnology activities distributed in: Revenues from the EU Agriculture 64.8 % International revenues related to biotechnology activities distributed in: Revenues from the EU Industry and Construction 57.1 % International revenues related to biotechnology activities distributed in: Revenues from the EU Services 44.8 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Total companies 44.8 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Agriculture 35.2 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Industry and Construction 42.9 % International revenues related to biotechnology activities distributed in: Revenues from the rest of the world Services 55.2 % International revenues related to biotechnology activities by classification: International trade in goods and services Total companies 87.2 % International revenues related to biotechnology activities by classification: International trade in goods and services Agriculture 95.7 % International revenues related to biotechnology activities by classification: International trade in goods and services Industry and Construction 90.0 % International revenues related to biotechnology activities by classification: International trade in goods and services Services 71.8 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Total companies 4.6 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Agriculture 4.3 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Industry and Construction 2.9 % International revenues related to biotechnology activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain Services 13.5 % International revenues related to biotechnology activities by classification: Subsidies from external sources Total companies 4.3 % International revenues related to biotechnology activities by classification: Subsidies from external sources Agriculture 0.0 % International revenues related to biotechnology activities by classification: Subsidies from external sources Industry and Construction 4.0 % International revenues related to biotechnology activities by classification: Subsidies from external sources Services 6.1 % International revenues related to biotechnology activities by classification: Other Total companies 3.9 % International revenues related to biotechnology activities by classification: Other Agriculture 0.0 % International revenues related to biotechnology activities by classification: Other Industry and Construction 3.1 % International revenues related to biotechnology activities by classification: Other Services 8.6