Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;1.040 No. of companies carrying out R&D in Biotechnology;250 or more employees;93 No. of companies carrying out R&D in Biotechnology;Total;1.133 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;32 %Companies according to biotechnology used: Genetic code;250 or more employees;43 %Companies according to biotechnology used: Genetic code;Total;33 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;40 %Companies according to biotechnology used: Functional units;250 or more employees;51 %Companies according to biotechnology used: Functional units;Total;41 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;22 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;41 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;24 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;48 %Companies according to biotechnology used: Bioprocesses;250 or more employees;69 %Companies according to biotechnology used: Bioprocesses;Total;50 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;5 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;12 %Companies according to biotechnology used: Sub-cellular organisms;Total;6 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;24 %Companies according to biotechnology used: Bio-computing;250 or more employees;28 %Companies according to biotechnology used: Bio-computing;Total;24 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;13 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;13 %Companies according to biotechnology used: Nanobiotechnology;Total;13 %Companies according to biotechnology used: Other;Fewer than 250 employees;15 %Companies according to biotechnology used: Other;250 or more employees;8 %Companies according to biotechnology used: Other;Total;14 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;581 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;22 Companies in which biotechnology activities are: Main and/or exclusive;Total;603 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;155 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;18 Companies in which biotechnology activities are: A secondary line of business;Total;173 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;305 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;53 Companies in which biotechnology activities are: A tool necessary for production;Total;357 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;45 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;49 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;45 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;19 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;3 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;18 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;30 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;39 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;31 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;23 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;17 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;22 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;17 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;14 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;13 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;9 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;12 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;8.124 Personnel in R&D in biotechnology (no. of persons);250 or more employees;3.386 Personnel in R&D in biotechnology (no. of persons);Total;11.510 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;4.552 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1.650 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;6.202 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;3.572 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;1.736 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;5.308 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;4.363 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;2.026 Personnel in R&D in biotechnology (no. of persons): women;Total;6.389 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2.368 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;935 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;3.304 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1.995 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;1.090 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;3.086 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;5.788,1 Personnel in R&D in biotechnology (FTE);250 or more employees;2.448,9 Personnel in R&D in biotechnology (FTE);Total;8.236,9 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;3.364,3 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;1.231,9 Personnel in R&D in biotechnology (FTE): Researchers;Total;4.596,1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;2.423,8 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;1.217 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;3.640,8 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;3.197,5 Personnel in R&D in biotechnology (FTE): women;250 or more employees;1.501 Personnel in R&D in biotechnology (FTE): women;Total;4.698,5 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1.803,7 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;708,8 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2.512,5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1.393,8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;792,2 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;2.186 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;558.184 Internal expenditure on R&D (thousands of euros);250 or more employees;211.247 Internal expenditure on R&D (thousands of euros);Total;769.431 1) By nature of the expense: Current expenses;Fewer than 250 employees;518.032 1) By nature of the expense: Current expenses;250 or more employees;201.684 1) By nature of the expense: Current expenses;Total;719.715 1.1) Remuneration to researchers;Fewer than 250 employees;154.555 1.1) Remuneration to researchers;250 or more employees;66.892 1.1) Remuneration to researchers;Total;221.447 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;72.617 1.2) Remuneration to technicians and assistants;250 or more employees;50.192 1.2) Remuneration to technicians and assistants;Total;122.809 1.3) Other current expenses;Fewer than 250 employees;290.860 1.3) Other current expenses;250 or more employees;84.599 1.3) Other current expenses;Total;375.459 2) By nature of the expense: Capital expenses;Fewer than 250 employees;40.152 2) By nature of the expense: Capital expenses;250 or more employees;9.563 2) By nature of the expense: Capital expenses;Total;49.715 2.1) Land and buildings;Fewer than 250 employees;6.661 2.1) Land and buildings;250 or more employees;2.860 2.1) Land and buildings;Total;9.521 2.2) Equipment and instruments;Fewer than 250 employees;24.465 2.2) Equipment and instruments;250 or more employees;6.001 2.2) Equipment and instruments;Total;30.466 2.3) Acquisition of specific R&D software;Fewer than 250 employees;1.157 2.3) Acquisition of specific R&D software;250 or more employees;653 2.3) Acquisition of specific R&D software;Total;1.810 2.4) Otros productos de propiedad intelectual específicos para I+D;Fewer than 250 employees;7.869 2.4) Otros productos de propiedad intelectual específicos para I+D;250 or more employees;49 2.4) Otros productos de propiedad intelectual específicos para I+D;Total;7.919 1.1) By origin of the funds: Own funds;Fewer than 250 employees;385.847 1.1) By origin of the funds: Own funds;250 or more employees;105.066 1.1) By origin of the funds: Own funds;Total;490.913 1.2) By origin of the funds: From companies;Fewer than 250 employees;53.140 1.2) By origin of the funds: From companies;250 or more employees;29.409 1.2) By origin of the funds: From companies;Total;82.548 1.3) By origin of the funds: Public Administration funds;Fewer than 250 employees;64.168 1.3) By origin of the funds: Public Administration funds;250 or more employees;32.641 1.3) By origin of the funds: Public Administration funds;Total;96.809 1.4) By origin of the funds: From Universities;Fewer than 250 employees;197 1.4) By origin of the funds: From Universities;250 or more employees;0 1.4) By origin of the funds: From Universities;Total;197 1.5) By origin of the funds: From non profit private institutions;Fewer than 250 employees;588 1.5) By origin of the funds: From non profit private institutions;250 or more employees;4.177 1.5) By origin of the funds: From non profit private institutions;Total;4.766 1.6) By origin of the funds: Foreign funds;Fewer than 250 employees;54.244 1.6) By origin of the funds: Foreign funds;250 or more employees;39.954 1.6) By origin of the funds: Foreign funds;Total;94.197 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;68.331 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;51.951 Purchase of R&D services in biotechnology (thousands of euros);Total;120.281 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;22.667 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;46.897 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;69.564 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;45.664 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;5.054 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;50.718 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;47 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;23 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;45 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;12 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;14 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;11 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;16 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;19 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;18 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;15 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;37 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;29 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;37 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;53 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;39 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;52 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;20 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;14 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;20 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;17 % Companies that have requested biotechnology patents in Biotechnology;Total;15 Number of patents requested;Fewer than 250 employees;525 Number of patents requested;250 or more employees;156 Number of patents requested;Total;681 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;24,9 % Companies with income of an international origin related to biotechnological activities;250 or more employees;18,4 % Companies with income of an international origin related to biotechnological activities;Total;24,3 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;6 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;1 % Turnover representing income of an international origin related to biotechnological activities;Total;1 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;45,2 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;73,1 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;59,6 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;54,8 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;26,9 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;40,4 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;89 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;72,5 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;80,4 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;7,5 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;24,9 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;16,5 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;2,2 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;2,3 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;2,2 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;1,4 % Income of an international origin related with activities according to the classification: Other;250 or more employees;0,4 % Income of an international origin related with activities according to the classification: Other;Total;0,9